ID E8R6W6_ISOPI Unreviewed; 321 AA.
AC E8R6W6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:ADV64309.1};
GN OrderedLocusNames=Isop_3753 {ECO:0000313|EMBL:ADV64309.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OG Plasmid pISOP01 {ECO:0000313|EMBL:ADV64309.1,
OG ECO:0000313|Proteomes:UP000008631}.
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV64309.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of plasmid of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV64309.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RC PLASMID=pISOP01 {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; CP002354; ADV64309.1; -; Genomic_DNA.
DR RefSeq; WP_013555159.1; NC_014957.1.
DR AlphaFoldDB; E8R6W6; -.
DR KEGG; ipa:Isop_3753; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_1_7_0; -.
DR InParanoid; E8R6W6; -.
DR OrthoDB; 258549at2; -.
DR Proteomes; UP000008631; Plasmid pISOP01.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Plasmid {ECO:0000313|EMBL:ADV64309.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008631}.
FT DOMAIN 15..252
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 321 AA; 34105 MW; 19BB06404CA58803 CRC64;
MTTITIATPT APRRALVTGG AGFIGSHLVE ALLARGWQVR VLDNFSSGQL ANLKPWLDRI
ELLEGDAADP VLAARACREV EVVFHQAAIP SVPKSVLDPI ATHHAGPTAT LTMLQAARAA
GARRFIFAAS SSAYGDTPTL PKHEAMLPQP LSPYAASKLA GEHYVAAFAR SMGLDGVSLR
YFNIFGPRQD PSSPYSGVIS RFHLVMSHGA PPTIYGDGTQ TRDFTAVANA VHANLLAADH
PQALRGAVLN VGTGQRTSLL DLVAALNRLL QLDPPLQPRY EPPRPGDIAH SLASLELVHA
TLGYQPLVSF EDGLRALVQS S
//
