ID E8RVA1_ASTEC Unreviewed; 808 AA.
AC E8RVA1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:ADU15242.1};
DE EC=3.2.1.23 {ECO:0000313|EMBL:ADU15242.1};
GN OrderedLocusNames=Astex_3614 {ECO:0000313|EMBL:ADU15242.1};
OS Asticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / KCTC 12464 /
OS NCIMB 9791 / VKM B-1370 / CB 48).
OG Plasmid pASTEX01 {ECO:0000313|EMBL:ADU15242.1,
OG ECO:0000313|Proteomes:UP000001492}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=573065 {ECO:0000313|EMBL:ADU15242.1, ECO:0000313|Proteomes:UP000001492};
RN [1] {ECO:0000313|Proteomes:UP000001492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15261 / DSM 4724 / KCTC 12464 / NCIMB 9791 / VKM B-1370 /
RC CB 48 {ECO:0000313|Proteomes:UP000001492};
RC PLASMID=pASTEX01 {ECO:0000313|Proteomes:UP000001492};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Teshima H., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Brun Y.V., Woyke T.;
RT "Complete sequence of plasmid 1 of Asticcacaulis excentricus CB 48.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP002397; ADU15242.1; -; Genomic_DNA.
DR AlphaFoldDB; E8RVA1; -.
DR KEGG; aex:Astex_3614; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_006501_0_1_5; -.
DR Proteomes; UP000001492; Plasmid pASTEX01.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR048230; GalA-like.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR040605; Glyco_hydro2_dom5.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR NCBIfam; NF041462; GalA; 1.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF18565; Glyco_hydro2_C5; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 2.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ADU15242.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADU15242.1};
KW Plasmid {ECO:0000313|EMBL:ADU15242.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001492};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..808
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003230143"
FT DOMAIN 82..222
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 233..332
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 340..417
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 423..585
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 632..688
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT DOMAIN 704..804
FT /note="Glycoside hydrolase family 2"
FT /evidence="ECO:0000259|Pfam:PF18565"
SQ SEQUENCE 808 AA; 90777 MW; 0D663D0D57828757 CRC64;
MASLPVLGMA TTLTPAATAA PEPNSPRQRL RLEDDWRFHF GHAEDLERDF GFGANQRTLA
KQGRSGAKPD AADYDDSTWR PVILPHDWAV ELPFVNNEDY RRNPADKDDE DYAAAHGYKP
IGRKFPETSV GWYRRLITLD KADAARCLWL EFDGVFRDAT IIFNGYVLER HDSGYTSFSV
DISDFINTDD TPNVLLVRVD ASYGEGWFYE GAGIYRHVWL VKADPVHVPQ WGVFVRPKTN
GMVEASVDLV NRSDARRVTT LDVTALDRDG TAVATTRQTV ELAAQSRATR EVRLTLPQPR
LWSIESPYLY TLRVEVTTEA TRDLYTLRFG LRDLRFDAQE GFFLNGKPLK IKGTNNHQDH
AGVGAAIPDA LQVWRLKQLK SLGSNAYRTS HNPPTPELLD ACDELGLLVI DEARQMTSSR
QGLSELEALI RRDRNHPSVI LWSIGNEEPQ QMTARGLKVA KSMARRIREL DPTRKVNAAM
NKGFGDGITT ALDVIGFNYH EAQIEPFRTR FPDMPIIGTE TASAVSTRGE YKTDAKRQVV
AAFDTEHPYW GATAESWWSL YNSKPYLLGG FIWTGFDYRG EPTPFNWWPS VASNFGVFDS
CGFPKDVYHY YRAWWQDEPV LHLLPHWNWS EGETVSVWAY SNCDEVELSL NSKSLGRQTM
RRDSHLEWTV PFTPGTLTAY GYKRGKVVMK TERKTAGAPH RLILSADRMQ LSADGQDVAM
VSVSAVDKVG TPVPLADDLI QFALTGPSRL IGVGNGNPNS HESDKAPYRR LFNGYAQAIV
QTTKTSGRFT FQARAEGLTA ASLTFTSR
//
