ID E8T3U8_THEA1 Unreviewed; 326 AA.
AC E8T3U8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Thiamine pyrophosphate TPP-binding domain-containing protein {ECO:0000313|EMBL:ADU97355.1};
GN OrderedLocusNames=Theam_1392 {ECO:0000313|EMBL:ADU97355.1};
OS Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1).
OC Bacteria; Aquificota; Aquificae; Desulfurobacteriales;
OC Desulfurobacteriaceae; Thermovibrio.
OX NCBI_TaxID=648996 {ECO:0000313|EMBL:ADU97355.1, ECO:0000313|Proteomes:UP000006362};
RN [1] {ECO:0000313|EMBL:ADU97355.1, ECO:0000313|Proteomes:UP000006362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15698 / JCM 12110 / HB-1
RC {ECO:0000313|Proteomes:UP000006362};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Vetriani C., Woyke T.;
RT "Complete sequence of chromosome of Thermovibrio ammonificans HB-1.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002444; ADU97355.1; -; Genomic_DNA.
DR RefSeq; WP_013538141.1; NC_014926.1.
DR AlphaFoldDB; E8T3U8; -.
DR STRING; 648996.Theam_1392; -.
DR KEGG; tam:Theam_1392; -.
DR eggNOG; COG1013; Bacteria.
DR HOGENOM; CLU_058423_0_0_0; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000006362; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd03376; TPP_PFOR_porB_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR PANTHER; PTHR42897:SF2; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 60..228
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 326 AA; 36482 MW; F17E85E1D5674EB1 CRC64;
MAQVNAAEVK IPPLKKLTNY PEKLAPGHRL CAGCGASIIV RQMYMAANAL GYELIIANAT
GCVEVCTSIY PYTSWRSPWI HNAFENAAAT IAGVEAAYKA LKRKGKLPSG KKVKFVALGG
DGGTYDIGFQ SLSGALERGH DFIYVCYDNE AYMNTGIQRS SATPKYANTT TQPVGSESLG
KPQHKKWMPE VAAAHGIPYV AQVAPSHWKD FMEKFKKALL TEGPSYINAF CVCPRGWRSK
EEEGILITKL AVETNYWPLF EVENGKWRIT YKPKNPKPVV EFLKKQGRFK HLFKPGNEDK
LAELQAEVDR RWEWLNKMEE LTNREG
//
