ID E8T6A9_THEA1 Unreviewed; 274 AA.
AC E8T6A9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Pseudouridine synthase {ECO:0000313|EMBL:ADU96693.1};
GN OrderedLocusNames=Theam_0726 {ECO:0000313|EMBL:ADU96693.1};
OS Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1).
OC Bacteria; Aquificota; Aquificae; Desulfurobacteriales;
OC Desulfurobacteriaceae; Thermovibrio.
OX NCBI_TaxID=648996 {ECO:0000313|EMBL:ADU96693.1, ECO:0000313|Proteomes:UP000006362};
RN [1] {ECO:0000313|EMBL:ADU96693.1, ECO:0000313|Proteomes:UP000006362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15698 / JCM 12110 / HB-1
RC {ECO:0000313|Proteomes:UP000006362};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Vetriani C., Woyke T.;
RT "Complete sequence of chromosome of Thermovibrio ammonificans HB-1.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC {ECO:0000256|ARBA:ARBA00010876}.
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DR EMBL; CP002444; ADU96693.1; -; Genomic_DNA.
DR RefSeq; WP_013537479.1; NC_014926.1.
DR AlphaFoldDB; E8T6A9; -.
DR STRING; 648996.Theam_0726; -.
DR KEGG; tam:Theam_0726; -.
DR eggNOG; COG0564; Bacteria.
DR HOGENOM; CLU_016902_4_4_0; -.
DR Proteomes; UP000006362; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0120159; F:rRNA pseudouridine synthase activity; IEA:UniProt.
DR GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IEA:UniProt.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 17..77
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 274 AA; 31892 MW; BA53D9920BA833FE CRC64;
MRRWKTERVE LRAKGGERLV ECVARRAGSK KRAKRLIDEG LVSVNGQKEL LARRRLKGGE
VVRFPLTEAP FKPPNVKLLF RERGVWVFEK PPFITTNEGE KSLEETVRKL FNPNLKVVHR
LDKQTTGPVI AVESEKLFEA FKKQFKRREV KKEYLCLVKG KLRSRQTVRR PIDGKSAVSL
VTPLEHFKRA TLCRVEIETG RKHQIRRHLA SVGYPVVGEF LYYRGSWPEE LLFCPRIALH
FRKLSFTHPA TGKRITVESE LPKDLKEFIG ELER
//
