ID E8TDR5_MESCW Unreviewed; 909 AA.
AC E8TDR5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Mesci_1804 {ECO:0000313|EMBL:ADV10958.1};
OS Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS WSM1271).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV10958.1, ECO:0000313|Proteomes:UP000007471};
RN [1] {ECO:0000313|Proteomes:UP000007471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC {ECO:0000313|Proteomes:UP000007471};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA Tiwari R.P., Woyke T.;
RT "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT WSM1271.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP002447; ADV10958.1; -; Genomic_DNA.
DR RefSeq; WP_013529647.1; NC_014923.1.
DR RefSeq; YP_004141008.1; NC_014923.1.
DR AlphaFoldDB; E8TDR5; -.
DR STRING; 765698.Mesci_1804; -.
DR KEGG; mci:Mesci_1804; -.
DR PATRIC; fig|765698.3.peg.2258; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_113_1_5; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000007471; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ADV10958.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 434..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 675..892
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 887..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 99438 MW; A13BE0956411880D CRC64;
MPDDRSSDTR PSPDALLDHA EREGRGRLRI FLGAAPGVGK TYEMLMSGRA RLADGVDVVI
GVVETHGRKE TLALVEGYEV IPRRKVDYKG RILDEMDIDA ILARRPALVL VDELAHTNAP
GSRHPKRYLD VQEILTHGID VYTTLNIQHV ESLNDVVAQI TKVRVRETVP DSIIDQADDV
EIIDLTPDDL IKRLEEGKVY FPNTAQRAIE NYFSPGNLTA LRELALRRTA QRVDDQLLIH
MQAHAIPGPW AAGERVLVCL DARPGGAARV RYARRLADRL RAPWTALHVD STRSASMPED
DKDRLATNLR LAQQLGAEVT TIPGQNVAQD IVRYATANNF THIVVGRPTR SRWRELIEGS
LTYDLIRNAG DISVHVISGS ERGTEAASRS VKAADEQRQF EIRPYLKATA FVIGSLAFAV
LLDQFLDVRN LAIILLIGVL ASAVTGGLWP ALYACFVSAL AFNYFFLEPR YTLTIRDPES
IVALGVFLVV AVIASNLTAR VQRQAVAARS RARATEDIYL FSKKLAGAGT LDDVLWATAF
QIASMLKLRV VLLLPEDGTI TVKAGYPPDD TLAEADIAAA RWAWEHNRAA GRGADTLPGA
KRLYLPLRTG RTAIGVVGLD NDKQGPLLTP EQQRLLDALA DQAAVAIERI QLVADVDRAK
LAAEADRLRS ALLTSISHDL KTPLAAIMGA AGTLRDFSAA LPEPDRAELL STVLDESERL
NRFIANLLDM TKIESGAMEP NYAFHYVGDI VGSALQRARK IIGEHKIETD IPRDLPMLKV
DPVLFEQALF NLLDNAAKYA PAGSTIRVQG WTDNGSVLLQ IMDEGPGIPP GDLERIFDTF
YRVRKRDQIR AGTGLGLSIC RGFIEAMGGT ITAANRTDGS GAVFTIKMPK PANPPNFDAS
NTDDVGDLA
//
