ID E8THY3_MESCW Unreviewed; 510 AA.
AC E8THY3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Major facilitator superfamily MFS_1 {ECO:0000313|EMBL:ADV11241.1};
DE Flags: Precursor;
GN OrderedLocusNames=Mesci_2089 {ECO:0000313|EMBL:ADV11241.1};
OS Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS WSM1271).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV11241.1, ECO:0000313|Proteomes:UP000007471};
RN [1] {ECO:0000313|Proteomes:UP000007471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC {ECO:0000313|Proteomes:UP000007471};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA Tiwari R.P., Woyke T.;
RT "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT WSM1271.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002447; ADV11241.1; -; Genomic_DNA.
DR RefSeq; WP_013529928.1; NC_014923.1.
DR RefSeq; YP_004141291.1; NC_014923.1.
DR AlphaFoldDB; E8THY3; -.
DR STRING; 765698.Mesci_2089; -.
DR KEGG; mci:Mesci_2089; -.
DR PATRIC; fig|765698.3.peg.2552; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_000960_28_2_5; -.
DR OrthoDB; 9791756at2; -.
DR Proteomes; UP000007471; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17321; MFS_MMR_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR42718:SF47; DRUG EFFLUX PUMP JEFA; 1.
DR PANTHER; PTHR42718; MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01036; TCRTETB.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..496
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 510 AA; 52800 MW; 2DEF75923257E36A CRC64;
MTSRTTTGSA ERWLVLLSVC LAAMTMPLTF TGPAVALSRI AADLGGSPIE LNWVTNAFML
TFGATLMASG ALADNHGRKR LFLVGLSLYI LASLGAMLAP DIIWFDIFRA VQGIGSAAAF
AGGASALAQE FEGPLRLRAF SFLGTSFGIG LAFGPIASGL LISAFGWRSI FLLVAALAIA
AAMLGLRTIR ESRDPDATGL DWAGAGTFTI ALASLTYGVL QAPQSGWADP LVVTLLAASI
ICFVAFVVVE RQAQRPMLDL TLFAYPRFVG VQFLAAAPAY AFVVLLVLLP IRFIGIEGMN
EIKAGQLMIC LSGPLLILPM LAGQLARWIA PATICGVGLL VAAAGLVWLS LTPPVDSALM
APLMLIGVGI ALPWGLMDGL AVSVVPRERA GMAVGIFNTT RVACEGVALA IVMATLSGFA
AAQLAAQGMA SSTDAAAAAQ LLVTGNLGEA AQHLPQAGAI VLVQAYETAF DRLLIVLAAI
TVVTALVVFL GLRRVSASER ETALPACQEG
//
