ID   E8V1I6_TERSS            Unreviewed;       678 AA.
AC   E8V1I6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   OrderedLocusNames=AciPR4_0345 {ECO:0000313|EMBL:ADV81181.1};
OS   Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4).
OC   Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC   Terriglobus.
OX   NCBI_TaxID=401053 {ECO:0000313|EMBL:ADV81181.1, ECO:0000313|Proteomes:UP000006844};
RN   [1] {ECO:0000313|EMBL:ADV81181.1, ECO:0000313|Proteomes:UP000006844}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC BAA-1853 / DSM 23119 / SP1PR4
RC   {ECO:0000313|Proteomes:UP000006844};
RX   PubMed=23450133; DOI=10.4056/sigs.3036810;
RA   Rawat S.R., Mannisto M.K., Starovoytov V., Goodwin L., Nolan M., Hauser L.,
RA   Land M., Davenport K.W., Woyke T., Haggblom M.M.;
RT   "Complete genome sequence of Terriglobus saanensis type strain SP1PR4(T),
RT   an Acidobacteria from tundra soil.";
RL   Stand. Genomic Sci. 7:59-69(2012).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; CP002467; ADV81181.1; -; Genomic_DNA.
DR   RefSeq; WP_013566914.1; NC_014963.1.
DR   AlphaFoldDB; E8V1I6; -.
DR   STRING; 401053.AciPR4_0345; -.
DR   KEGG; tsa:AciPR4_0345; -.
DR   eggNOG; COG3525; Bacteria.
DR   HOGENOM; CLU_007082_5_1_0; -.
DR   OrthoDB; 1098018at2; -.
DR   Proteomes; UP000006844; Chromosome.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000313|EMBL:ADV81181.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADV81181.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006844};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..678
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003232946"
FT   DOMAIN          29..159
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          163..473
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        319
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   678 AA;  75079 MW;  F88B9621405ED480 CRC64;
     MKYTRSLSVL AGAMALSTVA GVAQERLQIN LMPMPSEISF GTGSLSLAST FAVETPGTHD
     ARLEGAIGRA VRRLDFAAGL RHAGAGVVPG TKLVVKVQSP GEAVQSLNED ETYTLEVTST
     GAEIDAATDV GAMHGLETLI QLVQPSGEGY AIPAVHIHDT PRFRWRGLMV DCGRHFEPVP
     VLKRTLDGMA AVKLNVFHWH LTEDQGFRIE SKIYPKLTEK GSDGLFYTQQ DAREIVAYAR
     DRGIRVVPEF EMPGHSTAWL VAYPEMSSGT VPDGIRREFG VSNYAVDPTR DETYAFVDKF
     LGEMAEIFPD TYVHIGGDES PAPDWKTNPR IVAFMKKHDL KDNEALQAYF NTRVLKTVMR
     LHKHMMGWDE VLTPGLPKDV VVQSWRGTAS LVKGAKLGYQ GVLSAPYYLD GMRPASVHYL
     ADPLPSDADV TPEQRKLILG GEVTMWAEQL SERTIDSRIW PRTAAVAERF WSPENLRDVD
     DMYRRLERVS IELEGLGLTH LQSGDAGLRE LARTEQIDAL RTFASALEPV SFGERYKAQR
     TDQLTSLDRF VDAVRPDPPT KHWFEMLTKQ FLANPTGDAT DRAQMEAWLT RLSSTVPEVQ
     RQMKASPRLN DAALRATQMV KLTQTGKDAL NYLATGQKAP AGWKAKQLDL IAEAQKPSAI
     VRFTFIAALT DLVKAVSE
//