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Database: UniProt
Entry: E8W031_STRFA
LinkDB: E8W031_STRFA
Original site: E8W031_STRFA 
ID   E8W031_STRFA            Unreviewed;       256 AA.
AC   E8W031;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   28-FEB-2018, entry version 43.
DE   RecName: Full=Succinate dehydrogenase iron-sulfur subunit {ECO:0000256|RuleBase:RU361237};
DE            EC=1.3.5.1 {ECO:0000256|RuleBase:RU361237};
GN   OrderedLocusNames=Sfla_2393 {ECO:0000313|EMBL:ADW03822.1};
OS   Streptomyces pratensis (strain ATCC 33331 / IAF-45CD).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=591167 {ECO:0000313|EMBL:ADW03822.1, ECO:0000313|Proteomes:UP000002066};
RN   [1] {ECO:0000313|EMBL:ADW03822.1, ECO:0000313|Proteomes:UP000002066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33331 / IAF-45CD {ECO:0000313|Proteomes:UP000002066};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L.,
RA   Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I.,
RA   Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of chromosome of Streptomyces flavogriseus ATCC
RT   33331.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Succinate + a quinone = fumarate + a quinol.
CC       {ECO:0000256|RuleBase:RU361237}.
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:49601;
CC         Evidence={ECO:0000256|RuleBase:RU361237};
CC       Note=Binds 1 [2Fe-2S] cluster. {ECO:0000256|RuleBase:RU361237};
CC   -!- COFACTOR:
CC       Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC         Evidence={ECO:0000256|RuleBase:RU361237};
CC       Note=Binds 1 [3Fe-4S] cluster. {ECO:0000256|RuleBase:RU361237};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|RuleBase:RU361237};
CC       Note=Binds 1 [4Fe-4S] cluster. {ECO:0000256|RuleBase:RU361237};
CC   -!- SIMILARITY: Belongs to the succinate dehydrogenase/fumarate
CC       reductase iron-sulfur protein family.
CC       {ECO:0000256|RuleBase:RU361237}.
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DR   EMBL; CP002475; ADW03822.1; -; Genomic_DNA.
DR   RefSeq; WP_014154478.1; NC_016114.1.
DR   STRING; 591167.Sfla_2393; -.
DR   EnsemblBacteria; ADW03822; ADW03822; Sfla_2393.
DR   KEGG; sfa:Sfla_2393; -.
DR   PATRIC; fig|591167.6.peg.2457; -.
DR   eggNOG; ENOG4105E33; Bacteria.
DR   eggNOG; COG0479; LUCA.
DR   KO; K00240; -.
DR   OMA; DGQYFGP; -.
DR   OrthoDB; POG091H02OF; -.
DR   Proteomes; UP000002066; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   CDD; cd00207; fer2; 1.
DR   Gene3D; 1.10.1060.10; -; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR   InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR004489; Succ_DH/fum_Rdtase_Fe-S.
DR   InterPro; IPR025192; Succ_DH/fum_Rdtase_N.
DR   Pfam; PF13085; Fer2_3; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   SUPFAM; SSF54292; SSF54292; 1.
DR   TIGRFAMs; TIGR00384; dhsB; 1.
DR   PROSITE; PS51085; 2FE2S_FER_2; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   2Fe-2S {ECO:0000256|RuleBase:RU361237};
KW   3Fe-4S {ECO:0000256|RuleBase:RU361237};
KW   4Fe-4S {ECO:0000256|RuleBase:RU361237};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002066};
KW   Iron {ECO:0000256|RuleBase:RU361237};
KW   Iron-sulfur {ECO:0000256|RuleBase:RU361237};
KW   Metal-binding {ECO:0000256|RuleBase:RU361237};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002066}.
FT   DOMAIN       34    117       2Fe-2S ferredoxin-type.
FT                                {ECO:0000259|PROSITE:PS51085}.
FT   DOMAIN      158    180       4Fe-4S ferredoxin-type.
FT                                {ECO:0000259|PROSITE:PS51379}.
SQ   SEQUENCE   256 AA;  29248 MW;  17EC9B787990783F CRC64;
     MATPTLEKSD KAPEAGFADT PYITATFRIR RFNPEVSDEV EWQDFEISID PKERVLDALH
     KIKWEMDGTL TFRRSCAHGI CGSDAMRING KNRLACKTLI KDINPEKPIT VEAIKGLTVL
     KDLVVDMDPF FQAYRDVMPF LVTKGNEPTR ERLQSPEDRE RFDDTTKCIL CAACTSSCPV
     FWNDGQYFGP AAIVNAHRFI FDSRDEAGEQ RLEILNDRDG VWRCRTTFNC TDACPRGIEV
     TKAIQEVKRA LITRRF
//
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