ID E9AHC2_LEIIN Unreviewed; 358 AA.
AC E9AHC2; A0A2K4YXG8; A0A381MKS0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Putative radial spoke protein 3 {ECO:0000313|EMBL:CBZ08799.1};
GN ORFNames=LINJ_27_2530 {ECO:0000313|EMBL:CBZ08799.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CBZ08799.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CBZ08799.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08799.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CBZ08799.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08799.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JPCM5;
RA Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P.,
RA Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K.,
RA Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow genomic structural
RT differences between species and strains of Leishmania.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the flagellar radial spoke RSP3 family.
CC {ECO:0000256|ARBA:ARBA00006737}.
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DR EMBL; FR796459; CBZ08799.1; -; Genomic_DNA.
DR RefSeq; XP_003392623.1; XM_003392575.1.
DR AlphaFoldDB; E9AHC2; -.
DR SMR; E9AHC2; -.
DR STRING; 5671.E9AHC2; -.
DR GeneID; 10965959; -.
DR KEGG; lif:LINJ_27_2530; -.
DR VEuPathDB; TriTrypDB:LINF_270011200; -.
DR eggNOG; ENOG502QQSZ; Eukaryota.
DR InParanoid; E9AHC2; -.
DR OMA; QDEGWFA; -.
DR OrthoDB; 5481996at2759; -.
DR Proteomes; UP000008153; Chromosome 27.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR InterPro; IPR009290; Radial_spoke_3.
DR PANTHER; PTHR21648; FLAGELLAR RADIAL SPOKE PROTEIN 3; 1.
DR PANTHER; PTHR21648:SF0; RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG; 1.
DR Pfam; PF06098; Radial_spoke_3; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
SQ SEQUENCE 358 AA; 42119 MW; 7356D2D335A4DED8 CRC64;
MQRQVADSEV TVAAYTFRQP PQGFQEPKYR DPSSSRNASR YMHSGSQRYG NIMYDRRVYR
GNTYASPIMS IAARAEMEKR EMIDTQRRKQ ASQRAASIKR RKQLEAARRH MATPDPGEGR
YNTQIQTDEY LEELTDKVDQ QVQETQTDPL MDRPVTPKYV PIKSGRDAET QIHEGDLFRF
DEAVEPILEV LVGKTLEQAM LEVMQEEELE LLRQQQIEFE QRRKEELLET QKLEAEERRK
FEEKERRKKQ EMERIQREKE TREKLQARQF AKVYMSNMEN RVFSRLQDEG WFADRVLNEV
ELDFFPWLMT EVDRELAKKT KARALVDELI RDVVRLNASQ LEKSRAAAAA AGEGPVMA
//
