ID E9AHF8_LEIIN Unreviewed; 415 AA.
AC E9AHF8; A0A2K4YXL7; A0A381MML0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=LINJ_27_1080 {ECO:0000313|EMBL:CBZ08838.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CBZ08838.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CBZ08838.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08838.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CBZ08838.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08838.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JPCM5;
RA Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P.,
RA Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K.,
RA Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow genomic structural
RT differences between species and strains of Leishmania.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FR796459; CBZ08838.1; -; Genomic_DNA.
DR RefSeq; XP_003392659.1; XM_003392611.1.
DR AlphaFoldDB; E9AHF8; -.
DR STRING; 5671.E9AHF8; -.
DR GeneID; 10966126; -.
DR KEGG; lif:LINJ_27_1080; -.
DR VEuPathDB; TriTrypDB:LINF_270018400; -.
DR eggNOG; KOG0800; Eukaryota.
DR InParanoid; E9AHF8; -.
DR OrthoDB; 5474929at2759; -.
DR Proteomes; UP000008153; Chromosome 27.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46463:SF10; RING_U-BOX SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR46463; ZINC FINGER, RING/FYVE/PHD-TYPE; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
FT DOMAIN 215..255
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 415 AA; 44731 MW; 93F4582A5D84D714 CRC64;
MLSTMDSSAS PVCRSPSSKS YATRRVRSPV VLNLVEDNLK ESCSGEAFGS SQPASLTSSG
GGPRTSALSP SRMGKSVLTA EERENVLTTL TPNSRPRRKS DNAVTLSSSS SVRGSQEKGS
NSKLRAVKLC KFSALPQAPH TSANLDTCTS PVQRSVSSRR ARRSVSLTSS VLTSRPTEEL
AASSTPSNPP LMPELPAPLS SREHSAAISE EVDECCICLE VYTNENPMFR GACQHHFHLP
CLMEWKQRSS LCPMCCAETL RGIGEFEGSH QCAAADPAEV ARQRAIAKRD AEIAHNLQHN
YLLQAQLRGR QYAYATQAVR SFQGLHSGSP SSSTSRTPPH TAEVEEHPLS TLQAHNRCNA
QRSGGIVRQS PPPENVHQPR VTANAHSQLT APPAHPSMEE SRRSRSKSQA GCAVM
//
