ID E9C1W6_CAPO3 Unreviewed; 1173 AA.
AC E9C1W6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Cytohesin-4 {ECO:0000313|EMBL:KJE91175.1};
GN ORFNames=CAOG_002349 {ECO:0000313|EMBL:KJE91175.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE91175.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the BRAG family.
CC {ECO:0000256|ARBA:ARBA00006248}.
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DR EMBL; KE346362; KJE91175.1; -; Genomic_DNA.
DR RefSeq; XP_004349099.1; XM_004349049.2.
DR RefSeq; XP_011270158.1; XM_011271856.1.
DR AlphaFoldDB; E9C1W6; -.
DR STRING; 595528.E9C1W6; -.
DR EnsemblProtists; KJE91175; KJE91175; CAOG_002349.
DR GeneID; 14900417; -.
DR eggNOG; KOG0931; Eukaryota.
DR InParanoid; E9C1W6; -.
DR OrthoDB; 204547at2759; -.
DR PhylomeDB; E9C1W6; -.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR033742; IQSEC_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF406; MIP16918P; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF16453; IQ_SEC7_PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008743}.
FT DOMAIN 107..184
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 649..836
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 38..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 920..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1030..1062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..499
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1057
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1083..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1173 AA; 126219 MW; 17DAC3CDA0B0A48F CRC64;
MQDEVTQLKA RVAELEAERE SMAARIASLE TENARLTLQV AASPSSSAPE QASARATDGD
TPAQFMDESD CEPDSTEPAA PSSDEEQLNL AELAARATEL YELCHTPETG PLVADRTTKS
GVAMPRTFVA RELVSVLVKS GVAATRAQAV TLGRRLQSRS LIWHPASHNT VTFRDRTLLF
RFAVDATETD EQHKAHDQPK QQQQQEQQQE HEQEQEHEQQ AAAASEHASS LTQRAVFTIG
GVTESESGDN PSSKSSSNLN LSLPPHPLEA ERSVSVTELH ELLSPTRIEV QPPSLAPPSP
TRRHTSDPDL SMTLGDEALA SPSEKPGGLQ LPTATRRRAN TLTGRNSTHF ENIELSGDLQ
ELVRQGTLKR YLGGEHFEKA AITIQRFYRH HKLRTRFRDV VRRGLANSHS PAATVRTLTL
TGSLHSSLST SHESLPMVVD ITPMSARPSM ATALSPFLPS AGDTSSLVDN VSLTDNVSLA
DSDDDSSPSP HRSQAGDEDR GLVRSPSGSS LASQSSEALG AATESTDSGA ASPVPAKSAG
VSPSSSTNLS ASNSRPTMCQ RLLAQLRPLS FGPGHTLAVS SPGSDSSFDS FRSSGSGGSF
DSSTDASETS SLSVEGGLST PRTSKGSGTV APGTPAPSVP GQIDISHRTV SEDHAKTRQV
RIAIHKFNCD SKKGMLYLID KGFVLEKPRH VAFFLMRQPG LSKAMIGEYL GENKEFNLQV
LDCFSSMVEM SGKTFDEALR AYLSSFRLPG EAQKIDRMMN TFAQRYTQAN PEAFATVDAA
YVLAYSTVML NTDVHNPSVK HKMTQSDFVK NNRGINNNAD FPRVFLEGIY DRIASNEILA
GEDHVKEVER IAGNIVGNVP LLAIPQRHFV RMANFVEVLD VSQRIPKGKH IRTLYLFNDM
LLITKPSRST LTVPAHQIAP KPADKQAKGA PAPAPSSSAA HASNAVRTVS VPRFLFRNSF
PLLGLQIRLM TPTKYHNELF ELQDFHGTPL ILLKAEKPQE KLDFLSVLQD MIEENAEIDA
ERLAEMEKAL VTKSPSSSST HNAPFSTSSS PHGSSNALVD SDLKRAADVR SSKRFRMPFM
ANNKRTSLGS ASTMGLPPPS TTSLAPSTHS ETSVSLNDAD EKRSIVTSRS GGSLASSVST
ESTSSGAASN GSQTRSSEAI ATSTAPSPAT VQT
//
