ID E9CVF0_COCPS Unreviewed; 634 AA.
AC E9CVF0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Fimbrin {ECO:0000313|EMBL:EFW22095.1};
GN ORFNames=CPSG_02252 {ECO:0000313|EMBL:EFW22095.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL636487; EFW22095.1; -; Genomic_DNA.
DR STRING; 443226.E9CVF0; -.
DR VEuPathDB; FungiDB:CPSG_02252; -.
DR VEuPathDB; FungiDB:D8B26_002182; -.
DR eggNOG; KOG0046; Eukaryota.
DR HOGENOM; CLU_015284_3_0_1; -.
DR OMA; WQLMRKN; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21294; CH_FIMB_rpt1; 1.
DR CDD; cd21297; CH_FIMB_rpt2; 1.
DR CDD; cd21300; CH_FIMB_rpt3; 1.
DR CDD; cd21303; CH_FIMB_rpt4; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961:SF18; FI19014P1; 1.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002497}.
SQ SEQUENCE 634 AA; 71133 MW; 36221ED905215E75 CRC64;
MNIFKLQKKY PQFQQNEIFA LQDAFQRLDV DDKGYLDEAT VIKATQQSER QPYDVVRSAL
KEVELDSSRR VELEDYVDLI SKVRNASATA PPGSGSPARG HASKGSIGGK IHVQGSSANV
THTINEDERT EFTRHINAVL AGDPDIGHLL PFPTDTFEMF DECKDGLVLA KLINDSVPDT
IDERVLNRPG KKNKQLNAFH MTENNNIVIN SAKGIGCSVV NIGSGDIIEV REHLILGLIW
QVIRRGLLGK IDIKLHPELY RLLEEDETLE QFLRLPPEQI LLRWFNYHLK NANWDRRVAN
FSSDVKDGAN YTVLLNQLAP DLCSRKPLQT PDLLQRAEQV LQNAELLQCR KFLTPTSLVA
GNPKLNLAFV ANLFNNHPGL DPITEEDKFE VEDFDAEGER EARVFTLWLN SLDVQPAVNS
LFDDLRDGTI LLQAYDKVIP GSVNWRHVNK PPAHGGEMMK FKAVENTNYA IELGKQNRFS
LVGIQGADIT DGQRTLTLGL VWQLMRKDIT NTLSSLAKRM GKREITDGEM IQWANEMSRK
GGKSSSIRSF KDQAIGSGVF LLDVLNGMKS SYVDYELVTA GRTDDESYAN AKLAISIARK
MGATIWLVPE DICQVRPRLI TTFIGSLMAT FEKM
//
