ID E9D488_COCPS Unreviewed; 912 AA.
AC E9D488;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Dynamin GTPase {ECO:0000313|EMBL:EFW18881.1};
GN ORFNames=CPSG_04427 {ECO:0000313|EMBL:EFW18881.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL636491; EFW18881.1; -; Genomic_DNA.
DR AlphaFoldDB; E9D488; -.
DR STRING; 443226.E9D488; -.
DR VEuPathDB; FungiDB:CPSG_04427; -.
DR VEuPathDB; FungiDB:D8B26_001872; -.
DR VEuPathDB; FungiDB:D8B26_007100; -.
DR eggNOG; KOG0446; Eukaryota.
DR HOGENOM; CLU_008964_7_1_1; -.
DR OMA; QSKPWEG; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF149; GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11890)-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002497}.
FT DOMAIN 36..324
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 554..645
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 664..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 912 AA; 100773 MW; 2F57A0D3F4484B65 CRC64;
MALQSFDSDA LGQLQSEQSQ LLDAIDELRS LHLGHLVELP QLIVCGDQSS GKSSVLEAIS
RVRFPAKGGV CTRFATEVIL RRKPDSGIKV TIEPGPSRMD EEEKRRLRNF PTTLAPDTPL
STLIESAKEC MGISSTDERT AGFSDDVLKV EISGPDKPGL TLVDLPGLYH AKSKEQGAQG
IPIVRNLVKS YMSNQRSLIL AVISAKNEYN NQEVLDLAEK YDKKRERTLA IVTKPDTLPK
GSEEEQMYID LVNNERIKLQ LGWHALRNRD YDTRDISDGG RDEMEREFFS DGQWTNVPRG
YVGIDTLRPK LSTILLDHIS RSLPSLIKDI ESKICDRQAK LDQLGEERAT AGQKRSYLLN
VSSRFEKITS QAVNGIDSAT ITVADLEKEV SEMARKNRGI ELPGTSNQVL VGELFRDQSK
PWEGIAETYL TKVWRAIKDF TELLLLHLTE KATYRTLMSG ILNPALETMK ERALQKLQEL
VFHHKNGHPL PFDGEFLKSM DVRRQERRLA LLERKLLETS ASAANDKSKA IFSFRDIQKA
VSDLEEDSGN QFAAREIIDL MEVYYNMART TFIDNVAILV TENCLITPLQ TIFTALTVSN
MDDQEIRRLA AEPIYVQRNR EQFRSELSRL NAALKVCKHH ITGTEALFDT RVNGAPNLLQ
VVSERREGPT HSSSTADLSK DSTARIQNKE KNSAGLVSQK PIRTPSIFDT PPSAAPSDVK
TATNAVFQTN SSAPAPSTKK FDISGTCMES SGATKTAALA TSKSTSLFSN SSMFSFPRDV
ANLGNDSPGT KEDPSGFPPR HSGGFQYSGK PFGDVKTVSG SGFGSTPETG GFSFGNPVVS
AAAPKPHSGF GRPREETPST KGLGNGPYFE ERPTLYNGIC TDYFYSITSL LTNNSFEELR
LADYALEGLS PS
//
