ID E9D4I3_COCPS Unreviewed; 320 AA.
AC E9D4I3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:EFW18976.1};
GN ORFNames=CPSG_04522 {ECO:0000313|EMBL:EFW18976.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL636491; EFW18976.1; -; Genomic_DNA.
DR AlphaFoldDB; E9D4I3; -.
DR STRING; 443226.E9D4I3; -.
DR VEuPathDB; FungiDB:CPSG_04522; -.
DR VEuPathDB; FungiDB:D8B26_007040; -.
DR HOGENOM; CLU_076146_0_0_1; -.
DR OMA; EIGTPIW; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EFW18976.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:EFW18976.1};
KW Transferase {ECO:0000313|EMBL:EFW18976.1}.
FT DOMAIN 24..317
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 320 AA; 36308 MW; 4BB428CD6610AC3C CRC64;
MASSSSLVRL GQSIAGSASS SSPFLKLGQF LTGAVSTYTV TKQLGEFIWL GSNKVGQTVV
IKSARHFRIA NERDVLRKFQ SRTPHLRPLI DEIVEPADLP AIVLKHLEDD LLTALNAKLS
RREIKYASKR VLEALKVLHE DGYVHTDIKM DNVLVKYAPS SQNESGQRFT DVQLADLEST
VHITSRFCKD RDEIGTPIWR SPEAQLGLQW GPPTDIWSFG TMPKFPRGHD EYELEILAKY
HIYFGPYPPS YVDLADQETL GVLSLIMKDV PPEKLRPFSL ASQREISEDD KEFVLKIMKL
DPRDRPTAKE LLEDEWFNRI
//
