ID   E9D5M0_COCPS            Unreviewed;       783 AA.
AC   E9D5M0;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Fungal-type protein kinase domain-containing protein {ECO:0000259|Pfam:PF17667};
GN   ORFNames=CPSG_04900 {ECO:0000313|EMBL:EFW18214.1};
OS   Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN   [1] {ECO:0000313|Proteomes:UP000002497}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
RN   [2] {ECO:0000313|Proteomes:UP000002497}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA   Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA   Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA   Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Coccidioides posadasii strain Silveira.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL636492; EFW18214.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9D5M0; -.
DR   STRING; 443226.E9D5M0; -.
DR   VEuPathDB; FungiDB:CPSG_04900; -.
DR   VEuPathDB; FungiDB:D8B26_005049; -.
DR   eggNOG; ENOG502S5WB; Eukaryota.
DR   HOGENOM; CLU_005513_5_0_1; -.
DR   OMA; GESHECP; -.
DR   Proteomes; UP000002497; Unassembled WGS sequence.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR040976; Pkinase_fungal.
DR   PANTHER; PTHR38248:SF2; FUNK1 11; 1.
DR   PANTHER; PTHR38248; FUNK1 6; 1.
DR   Pfam; PF17667; Pkinase_fungal; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002497}.
FT   DOMAIN          272..684
FT                   /note="Fungal-type protein kinase"
FT                   /evidence="ECO:0000259|Pfam:PF17667"
FT   REGION          126..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          493..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..154
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        540..557
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   783 AA;  88800 MW;  37C0D3B69C5494E7 CRC64;
     MTELSPADCA IIEKCRLRNT SHNLHRRLEE ADQALRNPSP PRSDACQQAV LRLLYFLQGQ
     EAAFGLRSKT RDGSVASELA TLFRHVEGNF HYDHYRPLVQ LVLQKAPDTD IWKAVFDLIA
     TVTQVERSTP PPRPSLPILQ TPRSRNTSSL ANSSELRRDI DPVLTGELLG DLHGDIPGFY
     AAYFDDVEGL SSIAQAVFEN CKAGDSPLYR EESGWKDWPD NAVEKPVLEW LNEIIDQLIQ
     FAQDHDPSRK AARRPLAQPA KPIAGSTAKR KLDIGFVDDL HATPDKRYEW SQILVPGELK
     NDRKYDIPSG ARLDLARYAR EVLSAQDDRR FVLGFTLCGP LLRVWEFDRC GGIGSEETDI
     NKDGLQFIMV ILGFLFMDRP QLGFDPTIVT VDGRRCIEID RDGKKERLVI DEVILRAHCV
     AGRATTCWKA HRETDESRIP LVIKDSWQYP ERHEEGELLR EAMESGATRI ARYDFHETVQ
     VDGKDDNVQA IRKGLQVPKS KSKRGSLQVA LRGSASNRGS QSSAISRKRS SDCVDTIPPP
     PSKRTQSSSL TKHLTDSSPP NRVHRRVIVQ DYGKPIYESS SRVALLIGME GCIVGYESLY
     SKARLIQSDI SPRNLLVNEE DDNPSWRSFL IDLDLAIRVE RDGFSGARGK TGTRAFMAIG
     VLYGEKHSFM HDLESFFWVL FWICVHYEGP GRARHVEDFE KWNYMNTRDL AGAKKGLISD
     ESDFLTTMDE YFTPYYQPLS RWVNRLRRVV FPNGGRWKKT NSSLGSEMRK VLRDAQKDPE
     VID
//