ID E9DGY6_COCPS Unreviewed; 1009 AA.
AC E9DGY6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Kinesin family protein {ECO:0000313|EMBL:EFW14497.1};
GN ORFNames=CPSG_09085 {ECO:0000313|EMBL:EFW14497.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; GL636506; EFW14497.1; -; Genomic_DNA.
DR STRING; 443226.E9DGY6; -.
DR VEuPathDB; FungiDB:CPSG_09085; -.
DR VEuPathDB; FungiDB:D8B26_008342; -.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_001485_24_0_1; -.
DR OMA; YYDNVFT; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF36; CENTROMERE-ASSOCIATED PROTEIN E; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000002497}.
FT BINDING 324..331
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1009 AA; 108879 MW; EC90923EBBF3DFD8 CRC64;
MTSTTPQPSR PTTNPPSTVL PPLPTGKLKR STPGPADARI PATHASSTKL RTPSAVKTAA
KSTIPSPTFN SNNATGRSPS MGHISNSPER AVRRAASVAA FPHPSKMASR ASLISSSSSL
YNLPTANSRP LDSSTPSGGL KSKKPHRIHT GITNNPNSSG VTAFQDSSGE DSSTQTGRST
EIRSSTLQSP TPSRSSSAQG STYSTSATTF DDCDDNGRRR REEPTAQPGT SKRGSKMKEG
KGNVIVSVRV RPDSTNNDSS KTEVEWLVDG RRSLVSYRGK EGGDYFYDNV FATHDTNAKV
YDACAKRLVR RVMEGYHGTV FAYGMTGTGK TFSMQGTATS PGVIPLAITD IFSYIRETPH
REFLLRVSYL EIYNEKIHDL LSTPASAGIG PGAGQQEEIK LREDSKRGVY ATPLKEEIVQ
SPTQLLRVIA RGDHARRTGS TQFNARSSRS HAVVQIVVES RERGAASTPG HERRTGLVPG
GVRVSTLSLI DLAGSERAAE NKERRTEGAH INKSLLTLGT VIARLSGDKD KATSHSDRDG
KHLPYRDSKL TRLLQPALSG NSLVSILCTI QIGSTGGNTA ANTHTNETLN TLKFAARAKN
NIVSHAKRAE EAHAGVSGDA GSRVLLERYR MEIQALRAQL EKQGKSHAEQ ESRLEEERFE
KEAETRHEEQ MLEMQLARTA LKERIEHLNR LILCSKSTGV NASGNFSLTG LQLRGFDLKS
LRSSGSHSAL GGLQLHRSRS TTSVKSGSGA PHDQGPSFGS GDYEEDTIGE FADGTASLQA
QINALQADLA DKNRYISTLE RRLLQARRSS HSRMSVGLSQ LKAGGSSPCD PEIAALLREK
DMEIADLRLQ LDDKDRMVAA LRSAARQREI AQLAAESLPP DPPKPPSIPL RGHRPNHLSF
ESTSSPIMGP APAPAGSPVN LLSPTKIVEK DRDKKRRSVD EMSRMLDEMI QDRVESGHLV
KGMRGSVRLA SGLRKETSLE ATSPSPTNAP PMFERIAAPL QEVADAALS
//
