ID E9DJR0_COCPS Unreviewed; 1204 AA.
AC E9DJR0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Helicase C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51194};
GN ORFNames=CPSG_10059 {ECO:0000313|EMBL:EFW13350.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL636522; EFW13350.1; -; Genomic_DNA.
DR AlphaFoldDB; E9DJR0; -.
DR STRING; 443226.E9DJR0; -.
DR VEuPathDB; FungiDB:CPSG_10059; -.
DR eggNOG; KOG4439; Eukaryota.
DR HOGENOM; CLU_289183_0_0_1; -.
DR OMA; AMIDESH; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45626:SF17; HELICASE-LIKE TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002497}.
FT DOMAIN 1027..1192
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 99..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1204 AA; 135921 MW; ED262E82F4CB71B5 CRC64;
MNETHAKAML GLTAEELLDL KKVMQELHDK EIQGLIHQAV AKRVLKESRI AVVERAISQG
SFANKVLQAW ESESNRENVR GALVWLLVQV QYQKTRRQRY GIQQDSSPEP ASPRISSSTP
VRQPLLATAA SRPTSSLSAL ESLETCPTTS STPWYVPGLA KPLTPAAKEL YRAIIFTRNT
VSGSVSVCQV NELPSHRTLD RQGTLSEEDW TEWQSILTAD CEFCCDSQTI KSPDEQVTII
NKRLWQSVCV MQLEEILSKG TDGSLTLKFV ITARDTEPTH TREIQKRQIE SVTGPNNDGN
MSEGPETEFL DDDGHHDMPA TRRRRITTRS PSPATLSSSR PLSQHNQDSP QDSMRVDTTV
DEPHCDREDG FNGIDSMASH PDTPMDLDTV IDPPNPGAVP TASTEAQDPQ DGPTQVMDDR
ECDSTPAHIV VERPVSRTTS APTKDSEIQN EYPPASPSEI QKERRSPDVE MINGDDTLPL
DTGYEFLDEV TQLGPEPQTS DEGNTEQVDP AELIKPGRFR CEQMDSQTWR DFTSFFMLPQ
NENDGTDPTR KILIRGMLRD APPHQLYCAF WMLLKDQGLE QGGFIADEMG IGKTMEVILY
FVLGAWIIYN RLHIKQCRKD PAMANKHLPA VMDTEEGHKG PKQHHLRCPS QDMFPILCAC
VPDGVTARCL SQPLQGAMLV VVPKGLLLPW AREWADSIPG DSGNCLKLNL FIGHGDLTPT
KVGNLGHAFI QTAQHATLRQ HDLGPQQCYR HMFLTTPGSL SSRVMIPLHD IQKQDAQQLR
WRAVIRDECH QEKGFDSKTI RQFREINSAA GKQGYAQPPG YMLSWMTILA TAGWENDARL
QFAQHDQWKT LSARVQLLIS KKQLSRTDQI EFRSAAHQFG QVLECLMIRR TTETSWFNKP
IMELPPNRHH DVLCSLEPKV RDELQRREER EIQKLKDSYM RSLQEWKKHG QGSKPELSSQ
TFFKKSRINR IIAIFPALLD LMKTEQRELK LTDEEMMENG WHAGGDKEAP YIHAIDALAN
SSSKCRAIQH ILQGMGRDYR GRPEKIVILT EFPRVVHMLE MWLQKQGYCV AAVYSSMSVE
DRDTCINAFN RDLPLPGGET DASPGVLIST LEILGVGYTC VRAFRLILLS PSWLERDEAQ
GKARIRRYGQ MNEATYTYRL VCRDVQVESN ILDRQAMRKS FNELAMSLQR EVGIVPDIID
LDTV
//
