ID   E9DJW9_COCPS            Unreviewed;       784 AA.
AC   E9DJW9;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Fungal-type protein kinase domain-containing protein {ECO:0000259|Pfam:PF17667};
GN   ORFNames=CPSG_10118 {ECO:0000313|EMBL:EFW13307.1};
OS   Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN   [1] {ECO:0000313|Proteomes:UP000002497}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
RN   [2] {ECO:0000313|Proteomes:UP000002497}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA   Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA   Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA   Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Coccidioides posadasii strain Silveira.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL636525; EFW13307.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9DJW9; -.
DR   STRING; 443226.E9DJW9; -.
DR   VEuPathDB; FungiDB:CPSG_10118; -.
DR   VEuPathDB; FungiDB:D8B26_005407; -.
DR   HOGENOM; CLU_005513_5_0_1; -.
DR   OMA; TLIWELV; -.
DR   Proteomes; UP000002497; Unassembled WGS sequence.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR040976; Pkinase_fungal.
DR   PANTHER; PTHR38248:SF2; FUNK1 11; 1.
DR   PANTHER; PTHR38248; FUNK1 6; 1.
DR   Pfam; PF17667; Pkinase_fungal; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002497}.
FT   DOMAIN          272..685
FT                   /note="Fungal-type protein kinase"
FT                   /evidence="ECO:0000259|Pfam:PF17667"
FT   REGION          128..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          508..566
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        508..526
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        541..557
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   784 AA;  88588 MW;  D6B58586B7349AE5 CRC64;
     MAGLSSDEIA TVERYPLRNS LDRVRGLLQG AEQSHGDAAD GPDQTYQMAI SKALIALMDA
     KAAYNLRPPI SRLNIISELS RLLTCLQEGN YSHDHYRPLV QLVVQKAPDT DIWKAVYDLI
     ATVTYAEKST PPPRQSLPIL QTPRSRNTSS LANSSELRRD IDPVLREELL EDLHADVPDF
     YAAYFDDIEG LVSTAQAVFE NCKTGDSPLY RENGWKDWPD HADEKPVLKW LTEVIDQLVQ
     FAEIHDPSRT VVRRPLAKPA QPVAGSTAKR KLDIGFVDDP YATPDKRYEW SQILVPGELK
     NDRKYDIPSG ARLDLARYAR EVLSAQGDRR FVLGFTLCGP LLRVWEFDRC GGIGSEETDI
     NQDGLQFITV ILGFLFMNRR QLGFDPTVVT VDGRRCIEIE RDGKKEHLVI DGVILRARCV
     AGRATTCWKA HRQGDERTLV VKDSWQYPER DEEGELLREA MESGVTNVAR YYFHETVQVD
     GKDDDVRTIR KGLEVPPSKA KQVSLQVAMR TSASNRGRTG RSNGVGLKRS SDCVDTILPP
     PPSKRTQSSS PTKRLADSSP PNRVHRRVIV RDYGKPIYES SSRVALLVGM EGCIVGYESL
     YSRAGLIQSD ISPRNLLVNE DDDNPSWRSF LIDLDLAIRT QRDGFSGTRG KTGTRAFMAI
     GVLYGEKHSF MHDLESFFWV LFWICVHYEG PGKGRTVDDF EEWNYMNTEK LAGAKKGLIS
     DESDFLRIAD DNFTPYYRPL VPWVNRLRRT VFPNGGRWKE INPNLGSEMR KILQDAQEDT
     EVTD
//