ID E9DUF5_METAQ Unreviewed; 657 AA.
AC E9DUF5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=DNA replication complex GINS protein PSF2 {ECO:0000256|ARBA:ARBA00015139};
DE AltName: Full=DNA replication complex GINS protein psf2 {ECO:0000256|ARBA:ARBA00013969};
GN ORFNames=MAC_01253 {ECO:0000313|EMBL:EFY92617.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY92617.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY92617.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation.
CC {ECO:0000256|ARBA:ARBA00025163}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family.
CC {ECO:0000256|ARBA:ARBA00010565}.
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DR EMBL; GL698474; EFY92617.1; -; Genomic_DNA.
DR RefSeq; XP_007807593.1; XM_007809402.1.
DR AlphaFoldDB; E9DUF5; -.
DR STRING; 655827.E9DUF5; -.
DR GeneID; 19245564; -.
DR KEGG; maw:MAC_01253; -.
DR eggNOG; KOG4071; Eukaryota.
DR HOGENOM; CLU_513055_0_0_1; -.
DR InParanoid; E9DUF5; -.
DR OMA; VHILIMA; -.
DR OrthoDB; 2513241at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00067; GAL4; 1.
DR CDD; cd11712; GINS_A_psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR InterPro; IPR021858; Fun_TF.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR InterPro; IPR001138; Zn2Cys6_DnaBD.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF11951; Fungal_trans_2; 1.
DR Pfam; PF05916; Sld5; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
DR SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499}.
FT DOMAIN 45..73
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000259|PROSITE:PS50048"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 72330 MW; 5AB2837E426AF0FB CRC64;
MPDDSPVSDK QQLDQSTNKE TLMTSFPITK RKRATRAKFA KVRTGCVTCK RRHVKCDETK
PACKNCIKWA GFCGGYEPIL NQSKSSVKPA FVTPQSPEID GTSSPEEIDL TMYDSGYQFR
HPEDLSPPES IDSQVSSYGC LSCPPQPTAN CSIVPGSRLS LDNTFWTWNL PRLAHDNPAI
RHANMAVHAL LFSKGHTLAR VGKVAGRDHY GEALSCYGIA LQEARQATTG YIDLREAVIC
CMFFVIFETI NGDQEAAQAH LQSGQRILEE IDPEYNGVEG FRKELRNVLQ FLAQQARGSG
LDEANQREGD EGGSILDTLM TPTKTALRSF PDGFVSSFLA PRCLPTPMLG CSGCSGNANA
HPLPYSFKAG AHEVRSSRIT LRDRTRLTVA VPSTMALRLP PGLVPSEYVQ LRRRVAIAGR
MRRRIDPGEP IFNIVPRLRT NAETQGQTPQ LRPPRRSNLP LWLALLLKKQ RRANIVPPPW
MHPDSLRDVI HHETKVDTKG WAPPPPPRSR ADFMGNATRI NSFSGEETIL SPPFLPSCTA
DAPSGALPYH WFELAEMLLA QAVDDIASAS EVRSLLRDLQ EVRAAKMRSS TAQLESGVDG
VMSLRGVGAM ELAESRGFVT GVVEGVRTIG ASAEAMRREE EEQRRGDGEA SDDDMGL
//
