ID   E9E2J7_METAQ            Unreviewed;       308 AA.
AC   E9E2J7;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=Pre-mRNA-splicing factor 18 {ECO:0000256|ARBA:ARBA00018242};
GN   ORFNames=MAC_04095 {ECO:0000313|EMBL:EFY89886.1};
OS   Metarhizium acridum (strain CQMa 102).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN   [1] {ECO:0000313|EMBL:EFY89886.1, ECO:0000313|Proteomes:UP000002499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY89886.1,
RC   ECO:0000313|Proteomes:UP000002499};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
CC   -!- SIMILARITY: Belongs to the PRP18 family.
CC       {ECO:0000256|ARBA:ARBA00008137}.
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DR   EMBL; GL698495; EFY89886.1; -; Genomic_DNA.
DR   RefSeq; XP_007810435.1; XM_007812244.1.
DR   AlphaFoldDB; E9E2J7; -.
DR   STRING; 655827.E9E2J7; -.
DR   GeneID; 19248406; -.
DR   KEGG; maw:MAC_04095; -.
DR   eggNOG; KOG2808; Eukaryota.
DR   HOGENOM; CLU_039675_1_0_1; -.
DR   InParanoid; E9E2J7; -.
DR   OMA; SFAQVRW; -.
DR   OrthoDB; 199348at2759; -.
DR   Proteomes; UP000002499; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR   InterPro; IPR004098; Prp18.
DR   InterPro; IPR014906; PRP4-like.
DR   InterPro; IPR036285; PRP4-like_sf.
DR   InterPro; IPR039979; PRPF18.
DR   PANTHER; PTHR13007; PRE-MRNA SPLICING FACTOR-RELATED; 1.
DR   PANTHER; PTHR13007:SF19; PRE-MRNA-SPLICING FACTOR 18; 1.
DR   Pfam; PF02840; Prp18; 1.
DR   Pfam; PF08799; PRP4; 1.
DR   SMART; SM00500; SFM; 1.
DR   SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR   SUPFAM; SSF158230; PRP4-like; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT   DOMAIN          121..173
FT                   /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT                   /evidence="ECO:0000259|SMART:SM00500"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          47..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   308 AA;  35817 MW;  C7CB33A2FD5E9BC3 CRC64;
     MDFASLMNKE LSKAKTTNDA SKKYLKRSEI EEERKKAYLA EQKALEEERE AKAAAKRKRE
     EELAAENAAR EEKRRKLAEE SRKLREEREE EEERARRKRL GLPELVKKKE EDQGQAVEDD
     VPEEELREKL REIGHPAMLF GESHAAKLRR YRKLTTAMSK GPIPTTLELV EEKDMKVDGT
     VPADRDGRKW LFRQLASYFT MLFRKFESND VDDSLLIPVV QIVQALQERR YVDANDDYLR
     LSIGKAAWPI GVTMVGIHER SAREKLHNGE KGHVMGDEVT RKILQSIKRC LTFAQVRWPP
     TDLRQLMG
//