ID   E9E4C2_METAQ            Unreviewed;      1211 AA.
AC   E9E4C2;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 55.
DE   SubName: Full=KapL {ECO:0000313|EMBL:EFY89339.1};
GN   ORFNames=MAC_04720 {ECO:0000313|EMBL:EFY89339.1};
OS   Metarhizium acridum (strain CQMa 102).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN   [1] {ECO:0000313|EMBL:EFY89339.1, ECO:0000313|Proteomes:UP000002499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY89339.1,
RC   ECO:0000313|Proteomes:UP000002499};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; GL698501; EFY89339.1; -; Genomic_DNA.
DR   RefSeq; XP_007811060.1; XM_007812869.1.
DR   AlphaFoldDB; E9E4C2; -.
DR   STRING; 655827.E9E4C2; -.
DR   GeneID; 19249031; -.
DR   KEGG; maw:MAC_04720; -.
DR   eggNOG; KOG2020; Eukaryota.
DR   HOGENOM; CLU_003712_0_0_1; -.
DR   InParanoid; E9E4C2; -.
DR   OMA; IAKRSWG; -.
DR   OrthoDB; 2721902at2759; -.
DR   Proteomes; UP000002499; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045478; Exportin-5_C.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR   Pfam; PF19273; Exportin-5; 3.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002499}.
FT   DOMAIN          40..126
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          945..965
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        947..961
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1211 AA;  136385 MW;  1ACD6D7627065A3C CRC64;
     MSASSGNPSN GEDTEILRRI HQALDVVHSA SSGNEARRQA QSFLEEVKDI PEAPFQGYQL
     AADKTQPPVV RHYALSLLEH AIRYRWSTYN QEQATALRHW ILELSQSVSK EDASYLRKKT
     AQLWVEIAKR CWGSEWMDMD SLLVQLWQIQ DSAVHKELVL FILETLSDEV FTGDDSVVTM
     REGVLSKACV EIFTPTSVLV EAFPSRQPGP DVRHGPEGWL ERISQFLNYC VSSEAKDTAD
     AKSCAVKALS VFVSLMPWAI PKAIAAAQCV NVMTAGLASS HTDVQKASLE ALNALYYRSN
     FSDNEFRDLV APMYSPSSVD LCKGLYSWAT VDPEDIDEDK YQILKKLSEM LSYLGDYFER
     KFAQVPPEAA SSGFFGLLIQ VTQSPSLMVS IPILVTWTRI LGHRNLGPSN LVSENVGPLL
     DVCTSRLVRY ENLPENSTDP TYLFLLDDTD TIPERHAFLG NYRRYSSQII EQIVQLKLVD
     AVSYILGRTE HILQNLYDGQ PPFSKQTYTK HSTPALQVDS LFTVIEATLK GYVKWRRYHG
     RDHDPIIRKR ALQLLVFFST TALNKNAGFM LKVLEHILLT WPALEPEYRA YNDAIKDLQS
     ESMIELQRLA AEMPDHLLMK IQKLAEFVDP VKAQWQSEPI RTSLKSYADF CHYLGLDKAQ
     KYLASRRAHE LEDWGSCELD SEGLLLQNEL EERLKTLPLR PTKSFLAFSV ERLDKSSPAF
     QASYALWQQG FSNILADLLE YLKFAHATHN PDSWVELPTE MRGMVERVLS DRFWQAGISE
     GSKDDFYARV MDKKNTIEGL ASTIRGSVRF VRETAYAIIY CMSRLDLQFY GFSGLSGPLS
     EALFSDSIWL STHQQSNLLN LVRYLVDDCP VDYREQFLPQ LLAACFRQMD AKVNGEWERM
     EKQQTCVVDG EAGLKEEMKA ESILRQVTYT AVMMVADFLD PTKSNSHTLK SRSRKEGSED
     EPSTPYPSLR KFCLMRREIV EPLLVFCTHG IRMRDTRCCG MVLRLFISLV PEFQLVQGQG
     QYGSTGNVHD GKASSHTDTT PVPAEIASVI REYIAQDVLK ACLTSFHEPY FVEVQKELAS
     LIATIVVYYS PITSTPKDIL LSLPNVNPAE LDRLAPYMAK PGSHPRQQRA IVLELLKDLK
     GVSVSEMGKL AKTAGFGGSS RAKRSNRSKM AQGFMNTSNE ADGGVTRANG VMGARRTTPD
     ALEGVSNLFE G
//