ID E9E6Q7_METAQ Unreviewed; 436 AA.
AC E9E6Q7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=AP-2 complex subunit mu-1 {ECO:0000313|EMBL:EFY88346.1};
GN ORFNames=MAC_05555 {ECO:0000313|EMBL:EFY88346.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY88346.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY88346.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
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DR EMBL; GL698512; EFY88346.1; -; Genomic_DNA.
DR RefSeq; XP_007811895.1; XM_007813704.1.
DR AlphaFoldDB; E9E6Q7; -.
DR STRING; 655827.E9E6Q7; -.
DR GeneID; 19249866; -.
DR KEGG; maw:MAC_05555; -.
DR eggNOG; KOG0938; Eukaryota.
DR HOGENOM; CLU_026996_5_2_1; -.
DR InParanoid; E9E6Q7; -.
DR OMA; VWKIPRI; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd09251; AP-2_Mu2_Cterm; 1.
DR CDD; cd14836; AP2_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR043532; AP2_Mu_N.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR043512; Mu2_C.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR PANTHER; PTHR10529:SF236; AP-2 COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023176};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW Transport {ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 168..436
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 436 AA; 49069 MW; 419BE4007EFE73D0 CRC64;
MISGVLIFNQ KGENLIFRAF RNDCRPRLAD VFRIQVISNA QVRSPILTLG STTFSHVKHE
NIYLVAITKS NANAALVFEF LYRLIQLGKG YFGKFDEEAV KNNFVLVYEL LDEIIDFGYP
QNTETDTLKM YITTEGVKSE TRPEETSKIT MQATGALSWR KADVKYRKNE AFVDVIEDVN
LLMSATGAVL RADVSGQIVM RAYLSGTPEC KFGLNDRLLL DNDGLLTLPS GNRMGTKATK
AAAGSVSLED CQFHQCVKLG KFDTDRIISF VPPDGEFELM RYRATENVNL PFKVHAIVNE
VGRTKVEYSI GVKANFGSKL FATNVVVRIP TPLNTAKIVE RVTQGKAKYE PSENCIVWKI
GRFTGQSEYV LSAEAILTSM TNQRAWSRPP LSMNFSLLMF TSSGLLVRYL KVFEKSNYSS
VKWVRYMTRA GSYEIR
//
