ID E9E748_METAQ Unreviewed; 279 AA.
AC E9E748;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Threonyl/alanyl tRNA synthetase {ECO:0000313|EMBL:EFY88223.1};
GN ORFNames=MAC_05696 {ECO:0000313|EMBL:EFY88223.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY88223.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY88223.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Alax-L subfamily. {ECO:0000256|ARBA:ARBA00008429}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL698514; EFY88223.1; -; Genomic_DNA.
DR RefSeq; XP_007812036.1; XM_007813845.1.
DR AlphaFoldDB; E9E748; -.
DR STRING; 655827.E9E748; -.
DR GeneID; 19250007; -.
DR KEGG; maw:MAC_05696; -.
DR eggNOG; ENOG502S23F; Eukaryota.
DR HOGENOM; CLU_004485_3_0_1; -.
DR InParanoid; E9E748; -.
DR OMA; MPVEIDF; -.
DR OrthoDB; 5490212at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 2.40.30.130; -; 1.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR012947; tRNA_SAD.
DR PANTHER; PTHR43462; ALANYL-TRNA EDITING PROTEIN; 1.
DR PANTHER; PTHR43462:SF2; THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:EFY88223.1};
KW Ligase {ECO:0000313|EMBL:EFY88223.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499}.
FT DOMAIN 1..262
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 279 AA; 30824 MW; B144025EBE9B8363 CRC64;
MTVPGKTKLV YQYHGKLTEL ATKVHSVRSF GSLEDANRLL FKNGADDDFV VVTGETIFHP
QGGGQPSDQG FMNWSPNGTT AADLSFRVEA VRMDAVNGSQ VLHLGSFTTP AAASQLQPGD
RVKQVLDVEK RLLYSRLHTA GHVLGSAVRS LLETEIPGFD ELKASHFPDS AACEFRGAIE
GKWKEPIQRR VNEYLERSMP VEIDFWTEQD FCREGLERLI PDRSLLPPGE DKFRVVRIVG
AEVYPCGGTH VDTTDLCGET TVKKIARSKG ISRVSYTVT
//
