ID   E9EFR0_METAQ            Unreviewed;       516 AA.
AC   E9EFR0;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MAC_08708 {ECO:0000313|EMBL:EFY85248.1};
OS   Metarhizium acridum (strain CQMa 102).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN   [1] {ECO:0000313|EMBL:EFY85248.1, ECO:0000313|Proteomes:UP000002499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY85248.1,
RC   ECO:0000313|Proteomes:UP000002499};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617}.
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DR   EMBL; GL698584; EFY85248.1; -; Genomic_DNA.
DR   RefSeq; XP_007815048.1; XM_007816857.1.
DR   AlphaFoldDB; E9EFR0; -.
DR   STRING; 655827.E9EFR0; -.
DR   GeneID; 19253019; -.
DR   KEGG; maw:MAC_08708; -.
DR   eggNOG; KOG0157; Eukaryota.
DR   HOGENOM; CLU_020492_2_0_1; -.
DR   InParanoid; E9EFR0; -.
DR   OMA; DVWIPER; -.
DR   OrthoDB; 2727850at2759; -.
DR   Proteomes; UP000002499; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11051; CYP59-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR   PANTHER; PTHR24305:SF222; CYTOCHROME P450 MONOOXYGENASE STCS; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00022617};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002499}.
SQ   SEQUENCE   516 AA;  57826 MW;  3B9946F70EF72379 CRC64;
     MLAPLLVAAG ALLAAHLLRK LFVKRFEQYS GFPQHPSSLL LGHLQVVDEF VRKQPPKAHA
     DMAFAAMHEA LGRPPVMFVD LRPASSPMLV IGSYDVAEQI VKPSHRWPYT PPKVPEIWKR
     LEYLTGPRSI ISAKGDEWRA IRKRFNPGFA TPNLMNLLPS ILDKVSLFVE RLDSLASAGV
     EFPLQSYATD LTFDIIGRVA LDLDMDAQKK EPTEFMRVFR DLIETFSGEH LDLPWWCTPR
     VEWKRYRLHR WVRESLREIV RHRHAAGGQG ENNYSILAMS LQGVDSLSPD MVDLTCDQLT
     SFLFAGHDTT STLMSWAFYE LSRTPHALRA VRAELDDLFG PDPDPAAVRA TLLAPGGKEL
     LHRMSYTTAV IKETLRLWPP GATSRMTEPG DGFTVQTPTG ELCVDGLMIY QVHSIIQRDP
     EAFGDTANHF VPERWLHDSD KIPTGAWRPF ERGPRSCIGQ ELATIEARVV MALAARRFDF
     TKVGRGALAL DDAGAPEMGS HGQYNVASAM YMVGIF
//