ID E9ELV9_METRA Unreviewed; 1373 AA.
AC E9ELV9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Autoinducer 2 sensor kinase/phosphatase luxQ {ECO:0000313|EMBL:EFZ03544.2};
GN ORFNames=MAA_00618 {ECO:0000313|EMBL:EFZ03544.2};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFZ03544.2, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFZ03544.2, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFZ03544.2, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFZ03544.2}.
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DR EMBL; ADNJ02000007; EFZ03544.2; -; Genomic_DNA.
DR RefSeq; XP_007816807.2; XM_007818616.2.
DR GeneID; 19254904; -.
DR KEGG; maj:MAA_00618; -.
DR HOGENOM; CLU_000445_114_5_1; -.
DR OrthoDB; 1222064at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:EFZ03544.2};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:EFZ03544.2}.
FT DOMAIN 509..579
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 806..1029
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1106..1232
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 194..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1267..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 770..797
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 196..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1358..1373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1161
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1373 AA; 153038 MW; D95805CE6AC2D49A CRC64;
MASENLVEGN AASPDIAASV APIAAPDQVS QQHEHVIPLV DGDPKRPALE ALYATPTHHD
ETPRLSDGRR FLRDPLSLAH QGGRSQSQSP LRLPIPSITP GQLAFSAMQY LPVPVIVLNN
LKTVVLANEA MGRMMGLTSE TTSQDDATAA LEHLRGQTLS QIGIDMLQDG RPVWITWESF
LDSLVQEVGI RPPASHAQQP QVSQANPGDA TPTLDSSPIP ATEPRCPPMA LPSQDAVIEV
VVSRKDMNKT TYDSRYKARA SEYQAFAKMI ITVWEIENKQ TFFTLTFTNT TSAASSPPNT
KKLVAKPSVL EAADRRTIAI SAPSSVASSR DSNSPSFYSP GIVTMSSSPF PPMGPPSLAS
HSSTPSLLQK ITLMKDALLD NTQMPILAIW KDGSVIFPNK AARQLQSLDA DLDNCADGLD
LLRKWELWDE SFTRKLDVSE YPISILLRTE FPFASMRVGL VDRDGKKLIH DVLGEAIRDD
VTGEFLAAVV TGRDVTVITE QITQIKERDD ERFKLICDTM PQLVWTASPD GLHDFFNTRW
YSYTGLTPEE CLGMEWQMPF HPDDRHEALT RWKRSLETGE PFVTEYRCRS KEGEWRWFLG
RALAVRNKDS GNIEKWFGTC TDVHESIETK FDAKRTRQQL LSVIAHSQVT IFTVDTSRRV
NMLEGALIWN HTYEDVHDPS RWYIGENMHT VFNRLVDQLP EGEQLDFLQP IEDILEGRTT
EDVKQHGLDD RWYRTRFLPM YGKKTHDGKT TSDSTIEGVI GVIMDVTELR DREEALLKQS
REKRKAVANE AAAKEANRLK SQFLANMSHE IRTPITGVLG MAELLSHMDL DEEQRDYIDN
IQSSATSLLT VINDILDFSK VESGRLDVEE VQFSLSLVVK EVVRMLRFAV ERKNLDFQSD
IGSDIENDMV VIGDPGRVRQ IITNLLTNSI KFTNQGYVRF SVTTESETSD SINIKFVVED
TGIGIQEDVR KRLFQPFSQG DASTARRFGG TGLGLTICKN LLDLMHGRII LESTVDSGTK
ASFWIPFNKP HGPRKSHPVQ SGAIPDRLQS DLSISCNSSE YEQVGGTSTG SDGIGISSSI
PRRRLSVRTP PCVDQDMPRT ERAKTHILVV EDNPVNQMIA IKTIQKLGFQ VTAAWNGKEA
LEYLMATSRG QNMKPDMILM DVQMPIIDGY KCTHLLRHHS PYKTLLQDVP IVAMTASAIH
GDREKCNKAG MDDYLAKPVT MNILERMLIR WCLSRRKVSV TVEESSDCSQ ISEHCDNAGI
PHVGVEEQAT ESEQRVQDEP HGSPMTPRPF NTANGQPEPS PFDSPAAPGL NVQVRHQEGE
KELSSMLQEN KLIDAAGGPS FYRTPSFQGP SSGEALTEEN MKKLKSETSH LDR
//
