ID E9ET24_METRA Unreviewed; 674 AA.
AC E9ET24;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=DNA-binding domain-containing/ankyrin domain-containing protein {ECO:0000313|EMBL:EFZ01995.1};
GN ORFNames=MAA_03224 {ECO:0000313|EMBL:EFZ01995.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFZ01995.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFZ01995.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFZ01995.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFZ01995.1}.
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DR EMBL; ADNJ02000004; EFZ01995.1; -; Genomic_DNA.
DR RefSeq; XP_007819413.1; XM_007821222.1.
DR AlphaFoldDB; E9ET24; -.
DR GeneID; 19257510; -.
DR KEGG; maj:MAA_03224; -.
DR HOGENOM; CLU_009666_3_1_1; -.
DR OrthoDB; 3019647at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:UniProt.
DR GO; GO:0048315; P:conidium formation; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.10.260.10; Transcription regulator HTH, APSES-type DNA-binding domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036887; HTH_APSES_sf.
DR InterPro; IPR018004; KilA/APSES_HTH.
DR InterPro; IPR003163; Tscrpt_reg_HTH_APSES-type.
DR PANTHER; PTHR43828; ASPARAGINASE; 1.
DR PANTHER; PTHR43828:SF15; TRANSCRIPTION FACTOR MBP1; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF04383; KilA-N; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM01252; KilA-N; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54616; DNA-binding domain of Mlu1-box binding protein MBP1; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51299; HTH_APSES; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Conidiation {ECO:0000256|ARBA:ARBA00023321};
KW DNA-binding {ECO:0000313|EMBL:EFZ01995.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sporulation {ECO:0000256|ARBA:ARBA00022969};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 15..124
FT /note="HTH APSES-type"
FT /evidence="ECO:0000259|PROSITE:PS51299"
FT REPEAT 254..286
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 376..408
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 116..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 506..533
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 674 AA; 75577 MW; 5A37F001E40CA511 CRC64;
MVKAGVAAVS AGPGIYSATY SGIPVYEFQF GADLKEHVMR RRHDDWINAT HILKAAGFDK
PARTRILERD VQKDVHEKIQ GGYGKYQGTW IPLDSGEALA QRHSIYDRLR PIFEFVPGNE
SPPPAPRHAT KPKASKAKPA QPPPPPKWGA GAVMARHEEF DNGDTLMGED DTPDNLTVAS
ASYMADDDHF DMSHMSTSHR KRKREEHMQD LTEQQHAVYG DELLDYFLLS RNEQPAVKPD
PPPNFQPDWL IDAENHTALH WASAMGDVDV IKQLKRFNSN IAVKNIRGET PFMRSVNFTN
CYEKQSFPAV LKELFETVDS RDNSGCTVIH HAAVMKNGRV FSPSCSRYYL DLILNRLQEN
VDPSTFQQML DVQDNEGNTA LHLAAQRNAR KCIRALLGRN ASTDIANNEG IRAEDLIMEL
NAAKKERGPQ RSSSPFAPDS QRHASFRDAF ADNKKKPPAS FQSAAATTVQ SRIAPLLMEK
FQDLAKSYDD EWHEKDVAEA EARRILANTQ ADLHATHQQI AELEAQLETD DEATKIMGEA
NRCKHQVLSL ITHQNRLHIH QAVESDMNRV NGDNGENDSY DERLALARQL NSLIGELRQA
ENDYVDALSM VGTGDKIEKY RKLLKRCLDQ KDGEMLDSNL DNLIEMMEEE RDVNDVDGAM
VSAGDPMDFG VGGV
//
