ID   E9F363_METRA            Unreviewed;       281 AA.
AC   E9F363;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 2.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Fumarylacetoacetase, protein {ECO:0000313|EMBL:EFY97929.2};
GN   ORFNames=MAA_06712 {ECO:0000313|EMBL:EFY97929.2};
OS   Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS   anisopliae (strain ARSEF 23)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY97929.2, ECO:0000313|Proteomes:UP000002498};
RN   [1] {ECO:0000313|EMBL:EFY97929.2, ECO:0000313|Proteomes:UP000002498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
RN   [2] {ECO:0000313|EMBL:EFY97929.2, ECO:0000313|Proteomes:UP000002498}
RP   GENOME REANNOTATION.
RC   STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFY97929.2}.
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DR   EMBL; ADNJ02000011; EFY97929.2; -; Genomic_DNA.
DR   RefSeq; XP_007822901.2; XM_007824710.2.
DR   AlphaFoldDB; E9F363; -.
DR   GeneID; 19260998; -.
DR   KEGG; maj:MAA_06712; -.
DR   HOGENOM; CLU_028458_2_1_1; -.
DR   OrthoDB; 9433at2759; -.
DR   Proteomes; UP000002498; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR   InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR   PANTHER; PTHR11820:SF100; FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G01490); 1.
DR   Pfam; PF01557; FAA_hydrolase; 1.
DR   SUPFAM; SSF56529; FAH; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          71..278
FT                   /note="Fumarylacetoacetase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01557"
SQ   SEQUENCE   281 AA;  31382 MW;  28C680E89D400BF0 CRC64;
     MMPVFQRLVR FIASDGQIYY GEAGDDWQSE LVGRTVKVFT GLDPWAPDFE LSDQLATIQQ
     VICPLDKVPN VLGIGLNYRL HVKEAGFPMP SEPVLFSKAA DSLAGPYEDV PCHPVAKEVD
     WEGELCLVMG RDAKNIPEDQ DPLSYVLGYT VGNDVSSRYW QRPERCGGHF NYAKSFDKFS
     PVGPVIASLQ AVGNPEDLRL RTWVGNELMQ DGKTNDLIFD LRRIVRHCSN GTTLRRGTII
     MTGTPSGIGA TMTPSRFLKD QDVVKIEVER IGTIRNKMVF Q
//