ID E9F7V9_METRA Unreviewed; 909 AA.
AC E9F7V9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Steroid monooxygenase {ECO:0000313|EMBL:EFY96247.1};
GN ORFNames=MAA_08358 {ECO:0000313|EMBL:EFY96247.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY96247.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY96247.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY96247.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY96247.1}.
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DR EMBL; ADNJ02000001; EFY96247.1; -; Genomic_DNA.
DR RefSeq; XP_007824547.1; XM_007826356.1.
DR AlphaFoldDB; E9F7V9; -.
DR GeneID; 19262644; -.
DR KEGG; maj:MAA_08358; -.
DR HOGENOM; CLU_014803_0_0_1; -.
DR OrthoDB; 49786at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43098:SF5; DUAL-FUNCTIONAL MONOOXYGENASE_METHYLTRANSFERASE PSOF; 1.
DR PANTHER; PTHR43098; L-ORNITHINE N(5)-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 3.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:EFY96247.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 720..825
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
SQ SEQUENCE 909 AA; 101665 MW; 2F445C54E9614D43 CRC64;
MSKRVADYDA VVIGAGFSGI RSLWELDQLG LTVKCFDAAS DVGGTWYWNR YPGSRTDGEA
WVYILNFAPD LLEEWQYHER YPTQGEIQRY LSRIADRYNL RKYIEFGTRI AAASYSDAVN
IWTITTENGL STTCRYFLPA TGILSIPKKP PFPGLSSYTG EWYQASNWPA HEVDFYGKRI
AIIGTGSTGI HLLPKLAPIA KDVTVFQRTP NYVLPGRNHS IDEYQVVDIK KNHEATWELA
KMNIAGAACK ASGRTVKSVG DADKVRQILD HGWERGCFNF QLETFDDAFM DPESNEQVSE
FIRQKIRAIV QDPNKAELLC PKYPFGARRP PSGHFYYEAF NRPNVNLVDM SRDEIDLFEK
GVRTNSGAEY EFDMIIFALG FDAGTGAMNQ IDIKGSQGKV LKEYWNAERL GTFAGVLVSG
FPNMFIVCGP HMPAGNLPVP LELSVNWIGK TIRHMEENNL AVINVMEDAM HAWSDHHDGL
WNSVFISQPA KENRSWFVGT NIPGKPANIM FYFGGVQNWL LWLNKELDTN WESMEFTPLS
GTDKTDQDAP GQTFSSTTSS ITAEMLESAV MPLQSDQVGM TAAEKFNLGS AACARYIDWA
VKEMHDRGLA VKQDHRAYWW QVLQDFVKSE SGQVLIQQGP STKSEMDQLT SRLGIEGEAI
HRIGPELVRM LTGQTHPLAL ILRDDLLFRM YHSDEGARPN QYMADYAKFL CSKKKDLRIL
EIGAGTGGTT LKVLQACSPD GEFFCSEYMY TDISPGFFKT SRTTLKKWER VLKFQTLNVE
NDAAKQGFEE HAYDLIIAAN VVHATQSLTR SLGTIHKLLK PGGKLGLVEL TRLTPYFNMA
FGSLSGWWAG VGEGRTESPL QSPEQWGQHL QSAGFSGVDL AAYDLPEPES HSALLVSTAL
AVDVATNGY
//
