ID   E9F897_METRA            Unreviewed;       897 AA.
AC   E9F897;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=von Willebrand domain containing protein {ECO:0000313|EMBL:EFY96004.1};
GN   ORFNames=MAA_08496 {ECO:0000313|EMBL:EFY96004.1};
OS   Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS   anisopliae (strain ARSEF 23)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY96004.1, ECO:0000313|Proteomes:UP000002498};
RN   [1] {ECO:0000313|EMBL:EFY96004.1, ECO:0000313|Proteomes:UP000002498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
RN   [2] {ECO:0000313|EMBL:EFY96004.1, ECO:0000313|Proteomes:UP000002498}
RP   GENOME REANNOTATION.
RC   STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFY96004.1}.
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DR   EMBL; ADNJ02000003; EFY96004.1; -; Genomic_DNA.
DR   RefSeq; XP_007824685.1; XM_007826494.1.
DR   AlphaFoldDB; E9F897; -.
DR   GeneID; 19262782; -.
DR   KEGG; maj:MAA_08496; -.
DR   HOGENOM; CLU_003826_2_0_1; -.
DR   OrthoDB; 4178950at2759; -.
DR   Proteomes; UP000002498; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR   PANTHER; PTHR45737:SF6; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN DDB_G0286969-RELATED; 1.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
FT   DOMAIN          7..138
FT                   /note="VIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51468"
FT   DOMAIN          284..456
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          506..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          686..712
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          741..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        690..712
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        753..778
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   897 AA;  98121 MW;  00E4B82E6367BD6D CRC64;
     MSDQSMLCGC VVVADKTQRY LALAATSAHT TILSTTSRTR LTQTYVNNTG SIVKEARYMF
     PMYDGVSVVE FTCTIGPRVI RGVVRERQEA KRIFDRATAR GEAAGLLEQS LSASDVFIAK
     LGNVPAGEDV KVDVTYLGEL EHDAEIDGLR FTIPTAVAPR YGYHAYRDLV SAPEVRVQGK
     IAVTVDIDLG PGCIVKSVQS PSHPISVSIG TMSASVSQHP SPQMASASLS LGSAELEKDF
     TLQVVATGLG APAALLEIHP TKAHHRTIMA SLVPRFNLPV EKPEIVFICD RSGSMAGGKT
     MPNLISALNI FLKSLPVGVR FNICSFGWEC TFLWPKSVEY TQDTLNEAVR HVATFKADYG
     GTEMLAPVRK TFKKRIQESN LEVFLLTDGE IWDQDRLFHL INHEVAASKG AIRVFTLGIG
     WGVSHSLING AARAGNGFAQ VAGEDEKIDK KIVRMLKGAL TPHVSDYTLE IKYDKSEQDT
     APDSDTEADE FELVEKVVDS LTIDDAEEEA EEPGSKEAKP PTSLFDPSVK NEDLETKDAS
     EELDALETNL PPVDAPKYLQ TPSPIPALFP FNRTTVYIML SDETPAREPK SVVVRGTSRH
     GPLQLEIPIT KLGQTSTTLH QLAARKAVQE LEQGQGWLRH AKDAQGQPLR EKWPSKFPQV
     VKREAVRLGV EHQIAGKWCS FVATSSDANE EQETGDDSPV ALDEADEAGD DSCASLDEAD
     ELSDDDGVSY KSPVGRGRPM ATKAYRIATG PVEYDDDEEE EEEEDAEEEE EEEDNVGVAQ
     AEPDALSLLA NLQTYVGSWE WSLQLENVLG ITKAEAVSAI QFPIPADVED VLATLCAIAH
     LQKKMAADKE SWELMVDKAC SWVEDQVGRM EEELELLGYN GPVAWMRILM ALSVPPY
//