ID E9FS47_DAPPU Unreviewed; 321 AA.
AC E9FS47;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=DAPPUDRAFT_299840 {ECO:0000313|EMBL:EFX89968.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX89968.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX89968.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732523; EFX89968.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FS47; -.
DR STRING; 6669.E9FS47; -.
DR EnsemblMetazoa; EFX89968; EFX89968; DAPPUDRAFT_299840.
DR EnsemblMetazoa; XM_046608729.1; XP_046464685.1; LOC124210582.
DR KEGG; dpx:DAPPUDRAFT_299840; -.
DR eggNOG; KOG0027; Eukaryota.
DR HOGENOM; CLU_054826_1_0_1; -.
DR InParanoid; E9FS47; -.
DR OMA; HQENEND; -.
DR PhylomeDB; E9FS47; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0045202; C:synapse; IBA:GO_Central.
DR GO; GO:0043195; C:terminal bouton; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:1900271; P:regulation of long-term synaptic potentiation; IBA:GO_Central.
DR GO; GO:0099509; P:regulation of presynaptic cytosolic calcium ion concentration; IBA:GO_Central.
DR CDD; cd16179; EFh_HEF_CBN; 1.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR035799; EFh_CBN.
DR PANTHER; PTHR19972; CALBINDIN; 1.
DR PANTHER; PTHR19972:SF10; CALBINDIN-32; 1.
DR Pfam; PF00036; EF-hand_1; 1.
DR Pfam; PF13202; EF-hand_5; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 6.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 6.
DR PROSITE; PS50222; EF_HAND_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 44..79
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 93..129
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 140..175
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 186..221
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 233..268
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 277..312
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT COILED 166..193
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 321 AA; 37199 MW; F3EFAC49ACFB7221 CRC64;
MSSSAQNNTA AQQQLKNNIR INLDRCSNFM RQFRDPESRE LTKLSANQFM DVWSHYDKDA
NGYIEGTELD GFLAEFVSSV NIMDVGPEVV SDAMLAELKQ CFMEAYDDNQ DGKIDIRELA
QLLPMEENFL LLFRFDNPLD SSVEFMKIWR EYDSDGSGFI EADELKNFLR DLLTEAQRDK
EVTEDKLIEY TDTMLQVFDA NRDGKLQLSE MSKLLPVREN FLCRQVFKGP TVLSKDDIER
VFALYDRDNN GTIENEELRG FLKDLLELVK KDYDAQDLLD FEETILRGCD FNRDGKISKK
ELTMILLALS KHSQDDETKS K
//
