ID E9FT14_DAPPU Unreviewed; 1487 AA.
AC E9FT14;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFX89291.1};
GN ORFNames=DAPPUDRAFT_303147 {ECO:0000313|EMBL:EFX89291.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX89291.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX89291.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL732524; EFX89291.1; -; Genomic_DNA.
DR STRING; 6669.E9FT14; -.
DR EnsemblMetazoa; EFX89291; EFX89291; DAPPUDRAFT_303147.
DR KEGG; dpx:DAPPUDRAFT_303147; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_249356_0_0_1; -.
DR InParanoid; E9FT14; -.
DR OMA; LRGYCFD; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00033; CCP; 2.
DR CDD; cd00054; EGF_CA; 12.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR Gene3D; 2.10.25.10; Laminin; 17.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF111; FIBRILLIN-3; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 12.
DR Pfam; PF14670; FXa_inhibition; 4.
DR Pfam; PF02494; HYR; 1.
DR Pfam; PF00084; Sushi; 2.
DR PRINTS; PR00907; THRMBOMODULN.
DR SMART; SM00032; CCP; 2.
DR SMART; SM00181; EGF; 16.
DR SMART; SM00179; EGF_CA; 17.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 5.
DR PROSITE; PS00010; ASX_HYDROXYL; 11.
DR PROSITE; PS01186; EGF_2; 10.
DR PROSITE; PS50026; EGF_3; 13.
DR PROSITE; PS01187; EGF_CA; 5.
DR PROSITE; PS50825; HYR; 1.
DR PROSITE; PS50923; SUSHI; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 276..313
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 363..399
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 405..450
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 451..486
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 489..525
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 526..564
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 565..602
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 603..639
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 640..678
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 704..740
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 741..777
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 778..813
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 816..852
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 950..1001
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1002..1066
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1151..1233
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT REGION 21..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1313..1344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1382..1487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..52
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..155
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1395..1411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1472..1487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 455..465
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 530..540
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 782..792
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 972..999
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 1487 AA; 160969 MW; FC2D5A96A9845F6C CRC64;
MDECELEDVG QTCAGTCINT IGSFRCSEED DASSQEDRQD PENEEDDGEA AEAIQEAATS
SSTQTSTTTS TTSTTPTTTT TSTTPTPTTT STEATTTTSI PTTMEAITTT TTTTESPALI
PAEEEDEDEE NGEEEEGGEE ESEDGEEEEP EEPEDNKIDP ITTTTTPPPA AAVVETKEEE
KIPELEETCP EGFQLADRLA EAEDGSACLD VDECATEDQF GCSHLCVNTQ GSAHCDCPNG
WKMTNDGKTC RGNQFCKSSS QEFSIFKKMV GLDFPDIDEC STGNNFGCSH QCVNTDGSAH
CSCPSGYSLD ASDHKTCVDV DECSDQTQPN FGCSHHCVNL PGSAECKCTA GYKLRADQKT
CKDIDECAKE NGGCSHECVN LKGGMRCECP GGYRLSETDA KSCLDIDECA SLDEETQHSC
RATGGSCHNT LGSYQCICPE GFRSIGTACT DIDECAELSP CSTACTNLQG SYRCDCDDGF
ENVNGTCADI NECPNGVCDQ LCTNIPGSYI CDCHPGYQLI GDVCIDIDEC AIGNPCDDIC
RNTVGAFECL CAQGFQLNND DQCVDIDECL NDPCEGICIN TQGSYSCSCE LGYQLGDNGT
CSDVDECLSS PCPVECINSP GSFTCLCPFG YEFNDNVCKD IDECQKQPCG TNAKCINNEG
SFACQCEPGY ALRGRDCEEL VVYTEEEDRQ LCEYQKGVDL KKPDVDECKE NPCNGACINF
PGSYQCICDP GYELRDGRCE DIDECLNYKC GGRCTNLPGS YRCDCEKGYK LEGERCVDVD
ECVSLKPCKG SCINLPGSYR CDCNAGYQTE GNECIDIDEC SHRNGGCSHI CVNTVGSFRC
ACNPGFDVSH KNQSNCVDVN ECRSNNGGCS QDCINTRGAY HCTCSDQYYL EADGRTCIEL
PPRCPRMKVP DHGDMECTQN LNQTQHRSRE QEDEALIAEN GRGDLGASGR SANRSHKSRA
LYNTGSTCVI RCNKGYKLVG DSTISCGRSG LWIGEPATCI PLSCPKLLAP DNGALTPNTC
STGKTFAGQQ CQVRCRAGFR LIGGGTYHCL PSQQWRSPDE PARCERIDSP VPFIQCPGNM
AVNLPAQQNR AYVTFSQPKS NMDWFRYVDS DPLWAKQLGG ELPVGLNVIT FRVRSPVSDL
TAACNFTIEI FDKEIPRMTN CPSSLTVFLE PGQSSQIVTW NEPIFTDNIE IVQLNKSREP
GELFQSGYHE ITYVAQDGAG NQAKCQFTIH VTSPTVHRDT SSPITKLPRG RVLVRCPGIK
PGKYVEMYTY KVPAGCIVIN NPSAYTRATV TTLAPRYTVF DWDFGASGGD VDGRDSANSG
RHPTSHNKLV DGVPRLRDAG APSAPVIVPG PALIPSMGGG QTVRLSNGRA RKSRINEANL
QLLPNVPSGS NDPVDHRGNK NRNRDKKRGG VVDLLLPFTA NDAELQSPTT ARSGRKRQHG
PKHQPKLVPG PSFVPGNERN SKIKEKKEKN TAAGSTSNNR KNKTTAS
//
