ID   E9FTE8_DAPPU            Unreviewed;      1215 AA.
AC   E9FTE8;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 61.
DE   RecName: Full=Splicing factor 3B subunit 3 {ECO:0000256|ARBA:ARBA00040929};
GN   ORFNames=DAPPUDRAFT_303178 {ECO:0000313|EMBL:EFX89349.1};
OS   Daphnia pulex (Water flea).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC   Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX   NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX89349.1, ECO:0000313|Proteomes:UP000000305};
RN   [1] {ECO:0000313|EMBL:EFX89349.1, ECO:0000313|Proteomes:UP000000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21292972; DOI=10.1126/science.1197761;
RA   Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA   Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA   Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA   Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA   Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA   Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA   Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA   Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA   Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA   Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA   Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA   Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT   "The ecoresponsive genome of Daphnia pulex.";
RL   Science 331:555-561(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the RSE1 family.
CC       {ECO:0000256|ARBA:ARBA00038266}.
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DR   EMBL; GL732524; EFX89349.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9FTE8; -.
DR   STRING; 6669.E9FTE8; -.
DR   EnsemblMetazoa; EFX89349; EFX89349; DAPPUDRAFT_303178.
DR   KEGG; dpx:DAPPUDRAFT_303178; -.
DR   eggNOG; KOG1898; Eukaryota.
DR   HOGENOM; CLU_003246_0_0_1; -.
DR   InParanoid; E9FTE8; -.
DR   OMA; PRATGHW; -.
DR   PhylomeDB; E9FTE8; -.
DR   Proteomes; UP000000305; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 1.10.150.910; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   PANTHER; PTHR10644:SF1; SPLICING FACTOR 3B SUBUNIT 3; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT   DOMAIN          76..592
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          861..1181
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
FT   COILED          806..837
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1215 AA;  135409 MW;  D891CE308B64F9D6 CRC64;
     MYLYNLTLQR ATGIIQAVQG NFSGTKQQEI VIARGKVLEI VKPDPNTGKV HTLLSQEVFG
     IIRSIISFRL TGGNKDYLVV GSDSGRIVIL EYNAAKNVFD KVHQETYGKS GCRRIVPGQY
     MAIDPKGRAV MISAIEKQKL VYILNRDAQA HLTISSPLEA HKSNTLVYNI VGVDVGFENP
     VFACLEMDYE EADGDPTGEA AQKTQQTLTF YELDLGLNHV VRKYSEPLDE HANFLITVPG
     GNDGPSGVLV CSENYITYKN LGEQHDIRCP IPRRRNDLDD PERGMIFVCS ASHRTKAMFF
     FLVQTEQGDI FKITMDMDEE VVRELKIKYF DTVPVSSSMC VLKTGFLFVA SEFGNHYLYQ
     IAHLGDDDDE PEFSSTIPLE EGDTFFFAPR PLKNLVLVDE MESLSPVLAC HIADLANEDT
     PQLYALCGRS SRSSLRVLRH GLEVSEMAVS ELPGNPNAVW TVRKRADDEF DAYIVVSFVN
     ATLVLSIGET VEEVTDSGFL GTTPTLGCSS LGDNALLQVY PEGIRHIRAD RRINEWKSPG
     KRAISRCAVN QRQVVISLAG GELVYFEMDP TGQLNEYTER KEMTAEVVCM ALANVPSGEQ
     RSRFLAVGLA DNTVRVISLD PNDCLTPLSM QALPATPESL CIVEMGGHDK DSETTGTSGQ
     LFLNIGLQNG VLLRTVLDPV TGDLADTRTR YLGSRPVKLF RVMTQNHEAV LAISSRTWLS
     YYFQNRFHLA PLSYDSLEFA SGFASEQCPE GVVAIASNTL RILALEKLGA VFNQVSYPLE
     YTPRKFVVHD SGRMIIIETD HNAYTLETKL ERRQQIAQEM RDAATEEEQE LAHQMADAFL
     NEDLPESDFG APKAGAGMWA SIVRIMDPTS GNSLHTIRLP QNEAALSIGL ARFMNQDPED
     YFVLVGVAKD LKLNPKQCDG GFIYTYKLIN EWSALEFVHK TPVEDTPYAI CAYQGRVLIG
     VGRLLRLYDM GKKKLLRKCE NKHLPSCVVN IQALGQRVYV ADVQESIHFV RYKRMENQLI
     IFADDTHPRY VTTMCLLDYD TVAVADKFGN ISVLRLPSRT SDDVDEDPTG NKSFWDRGVL
     NGASNKAEVL CNIHIGETAL SLQRATLIPG GSESLVYTTL SGSIGVLVPF TSREDHDFFQ
     ALEMHLRSEH PPLCGRDHLA FRSFYFPVKN VIDGDLCEQF NSIDSSKQKA VADDLDRAPN
     EVSKKLEDIR TRYAF
//