ID E9FTT0_DAPPU Unreviewed; 203 AA.
AC E9FTT0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Homologous-pairing protein 2 homolog {ECO:0000256|ARBA:ARBA00016093};
GN ORFNames=DAPPUDRAFT_190785 {ECO:0000313|EMBL:EFX89589.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX89589.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX89589.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HOP2 family.
CC {ECO:0000256|ARBA:ARBA00007922}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL732524; EFX89589.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FTT0; -.
DR STRING; 6669.E9FTT0; -.
DR EnsemblMetazoa; EFX89589; EFX89589; DAPPUDRAFT_190785.
DR KEGG; dpx:DAPPUDRAFT_190785; -.
DR eggNOG; KOG4603; Eukaryota.
DR HOGENOM; CLU_063266_2_1_1; -.
DR InParanoid; E9FTT0; -.
DR OMA; QKYHREW; -.
DR PhylomeDB; E9FTT0; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0000794; C:condensed nuclear chromosome; IBA:GO_Central.
DR GO; GO:0120231; C:DNA recombinase auxiliary factor complex; IBA:GO_Central.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0120230; F:recombinase activator activity; IBA:GO_Central.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IBA:GO_Central.
DR GO; GO:0000709; P:meiotic joint molecule formation; IBA:GO_Central.
DR GO; GO:0010774; P:meiotic strand invasion involved in reciprocal meiotic recombination; IBA:GO_Central.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR010776; Hop2_WH_dom.
DR InterPro; IPR040661; LZ3wCH.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR15938:SF0; HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG; 1.
DR PANTHER; PTHR15938; TBP-1 INTERACTING PROTEIN; 1.
DR Pfam; PF18517; LZ3wCH; 1.
DR Pfam; PF07106; TBPIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000313|EMBL:EFX89589.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 10..70
FT /note="Homologous-pairing protein 2 winged helix"
FT /evidence="ECO:0000259|Pfam:PF07106"
FT DOMAIN 153..203
FT /note="Leucine zipper with capping helix"
FT /evidence="ECO:0000259|Pfam:PF18517"
FT COILED 89..153
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 203 AA; 22747 MW; FB91489476A8E710 CRC64;
MAKESKDKTS TAVLQYFIMQ NRPFAVNDLL QSAQLKDFGK AAVQKTLDQF VVAGKVMEKT
YGKQKVYAIN QDLVSSPDDL NITEIDAKIS ELTRQNAEDE AFIKKAESEL KILNSTLSIA
EATSQLKMLC KENETMESKL KDLSQNKVKL SAADFKKACV IKEKTASELR KRKRICGDML
DQILESYPKG KKALLEEVGV ETD
//
