ID E9FTW5_DAPPU Unreviewed; 372 AA.
AC E9FTW5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=DAPPUDRAFT_220591 {ECO:0000313|EMBL:EFX89438.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX89438.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX89438.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732524; EFX89438.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FTW5; -.
DR STRING; 6669.E9FTW5; -.
DR EnsemblMetazoa; EFX89438; EFX89438; DAPPUDRAFT_220591.
DR KEGG; dpx:DAPPUDRAFT_220591; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_714219_0_0_1; -.
DR InParanoid; E9FTW5; -.
DR OMA; PPHTVYP; -.
DR PhylomeDB; E9FTW5; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IBA:GO_Central.
DR GO; GO:0006066; P:alcohol metabolic process; IBA:GO_Central.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 17..365
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 372 AA; 40573 MW; A63E29502C6D104A CRC64;
MNRVCKQVSI ESPATVGMSK EYVFQYDVMV PDVPALGARV KVMCAGACYR QRSASVSSTS
STCSMGSDSG CTTSASHRGL RDSSFYPGYE VAGVVESIGE EVDPSCGIKV GDHVIVYPFD
ECPPGYAEYM SVPEIEFLVK IPDNMSLSVA AMLPSGALWA LNTVQKAESV VRRISEEKGP
EGMCHILVVG TGGLALWALR LARFFFSEKQ HRVHIAVACL RDEGFCLAQE SGKVDVIQWN
EELYERILIE RTKDACHGQV DVVIDFGTTS RSLNRSIQCL HKGGVVFLGH ETADRLLPKF
SRKAVEYGIT IEPVETGSVQ QLKELVDLVH SGKVKPPPHS VFPAEEASDV INKLCKSEIP
GRAILQFHSS AQ
//
