ID E9FWW1_DAPPU Unreviewed; 459 AA.
AC E9FWW1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=DAPPUDRAFT_305633 {ECO:0000313|EMBL:EFX88367.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX88367.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX88367.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732526; EFX88367.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FWW1; -.
DR STRING; 6669.E9FWW1; -.
DR EnsemblMetazoa; EFX88367; EFX88367; DAPPUDRAFT_305633.
DR KEGG; dpx:DAPPUDRAFT_305633; -.
DR eggNOG; ENOG502QS6C; Eukaryota.
DR HOGENOM; CLU_019379_1_0_1; -.
DR InParanoid; E9FWW1; -.
DR OMA; KFDESWW; -.
DR PhylomeDB; E9FWW1; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0030427; C:site of polarized growth; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IBA:GO_Central.
DR CDD; cd11959; SH3_Cortactin; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035716; Cortactin_SH3.
DR InterPro; IPR003134; Hs1_Cortactin.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10829; CORTACTIN AND DREBRIN; 1.
DR PANTHER; PTHR10829:SF23; CORTACTIN, ISOFORM A; 1.
DR Pfam; PF02218; HS1_rep; 4.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51090; CORTACTIN; 4.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 401..459
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..336
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 50618 MW; 1A66F1E3D34394EC CRC64;
MWKSAVGSSI KAPVVNQDDD EWDTDPNYIN NVTEEEQRWG GGRTAGAIDM NALREQTTKE
DLELKKKVMA AGPQASYGYG GKFGVQGDRM DKSAVGHDYV AKVEKHGSQT DAAKGFGGKF
GVQTDRVDKS AVGWDYQEKV EKHESQVDGN KGFGGKFGVQ ADRVDKSAVG YDYQEKVEKH
ESQVDGSKGF GGKFGVQTDR QDAAAVGFDE EQGHVGTTYE KDKPVIAEKG KASLLKSRFE
NFAEENKKAA MVVPPPPKNP RPMAKIAHKF ETQSTPQTEP PIKQIPQTEK PVRQNQFLPA
KSPVITEPVI RESPVISPVP EPARSPSPPP TVVPPVPAQT QQHIAQSLER WNDDLAEAVE
EVDDGAWREQ VDEQDDAWKD EEEIGYVQEN SNLETVAEET GSGLIAVALY DYQAAAEDEL
SFDPDEVIVN IEMIDEGWWR GECRGQIGLF PANYVQLQQ
//
