ID E9FZY4_DAPPU Unreviewed; 1911 AA.
AC E9FZY4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 03-MAY-2023, entry version 38.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=DAPPUDRAFT_236095 {ECO:0000313|EMBL:EFX87177.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX87177.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX87177.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732528; EFX87177.1; -; Genomic_DNA.
DR EnsemblMetazoa; EFX87177; EFX87177; DAPPUDRAFT_236095.
DR KEGG; dpx:DAPPUDRAFT_236095; -.
DR eggNOG; ENOG502SD1W; Eukaryota.
DR HOGENOM; CLU_002013_0_0_1; -.
DR InParanoid; E9FZY4; -.
DR PhylomeDB; E9FZY4; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46844; SLR5058 PROTEIN; 1.
DR PANTHER; PTHR46844:SF1; SLR5058 PROTEIN; 1.
DR Pfam; PF05729; NACHT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 710..849
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 1911 AA; 221290 MW; 64F27DC4B0FE2C63 CRC64;
MASRSDDLDT DTLDVERLTV SGTPNSPTKA INRPIAGSLF QLKLSSLFLI RGVTAKYQFH
LGTEVAHEGG KFDDVLFKYQ VSTGGTRQWR YRFLQAKHKQ NEIKNQITSE ALLDDDHGDF
SVSKYYRSYC REILNGSEGR RPEEIDDVII CTNINFNEAN LNAYGIELVP HNDPSDKILS
FEKLPGGKVP VRYKLKNTEV LRKKLNESSK KSKLYSLAKK LIDSENKNIC LSLTHELIKN
CHLALVKEKV IDLTTQRLHS DFIYGKNLSS DANELRRILR DFSMRKLIWK EDWKSCTFKL
DDGFGLGEEV QCLSGPEEEI DSFLDKFVFA VNTPNEVELD AIMKKELGKY YNLLVSDVQF
NHFSNTMLDW FKNKDSQWMT SDEGIRILEA IKEKVDQMRC AVLINYVNQI NKIAEITDTA
AQEMAEKLKP FLASSDKLEK INYIATDWPD FSALKVIAAI KTLPNFKFTD SYMVISSKHA
QKKEDFQGLR RMFSNGKAHH LLVIVCEDHS PINYDKYVNL VADSEEKKIL LIVKKGTDVR
PQLLINEDVI SYGQLSENFK NVLLSKKVSF QGKDMPVRDL IPPDKAENVL DWESIKMLAA
QNKIVVPSFN TTRFERSLYI KRRMALPFEF DSKFWENLAE DMKCSKTLLM SQCKVNAKSA
IVWSASEERK AEIWEKIKIK LSDRSTLGLP ANANISEDEL IFDKKWKNSA IVIISGGAGT
GKSTVLSHYC EAIKKAKPTR WITRINLVDH GEILSKFEPK MKDNSSNEED EEDFSTTTDF
FVDELNIRDC GDAFSRSLLR HQLKMGDNRV VVMLDGFDEI SSQLQEKVIH LMKAIIANKS
VQLIVTTRPH MMDQLQLQLS QLAYSLENFT EKDQIDYLSE YWETNLKELE DKSVVIRKFS
EYFVQRVSHT LKDKEKSFIG IPLQCRLMAE CFQSDLQGII KENRNDSEIQ KLLDGQKFDL
ATMYNRLMET KRRVFYEEKI SVSAPNQIVA YAIDGFIKKI EFHLTKLAIE TIFTDQGTVN
LLCPPNSQHQ SKFEKVAEEK AIAECGLKFG LTFLNGEKVQ FLHRTLAEYL VAKFFSQGFS
LDQEKHNGLL DKAVVRDLIF SVVMTKNNGI YDGVQMFFDS FLAELVDENE EWRNIIDKRL
KNKFPERFKS FMNGIINKRQ SVYVVDPNIL DVPIHQRNTS LFKFICDCLD MMIDPVRLRK
SMSSLFLVSC KFFYEQNSEA YKRLLSYFSS PSEFELNMIL DHILYYPMQI YLDDLFWNEG
EKKKILKVVL DFMGKNLATL KRILKDPSSN AEKQMKFALH FFMCNDYYDN ELKQYLELLS
SAYSSEPSFL SLFRATFNIS ESHFGSFQLN GKMEKTVVIL RNLGRIRVLE ALSHVVLLRD
PEVFRRYYEP SLSLDETDVV STNLHQLLAR DQYRMTRLDR SAFRGDTGAV DRILQTLRHS
LGPTETNEEV KKTAKEVVDD MVFRESQEFT SFFVAAAFGH EEICRKLLIF FKDLVNMKVL
PLKQLQDFYV APNGMIYNAT QLAIRFVKLP MFRLILTSVK QIMGQRPLVF LLKKFIWNNK
EWFETLAQIV VDGTDGTTGY QQLNEIVLQD SSTLEALRIV EEETFNQMVS VDGVEKWTKC
LLDIDLPKGF HLLSRHHLSH FDRTQMRSFI KTIITDSSGQ ENSYWDRLLL LSAQDFPCND
FEIDFDHILK CAWDKLVQGK ERLVLCRFNG ITGFLLSLTE SFWFYGDKSL GYRLLDFVKE
RQDEEVIRRM MKCMPTFLHY VMDPFGKIPV RGTVIQTRMK VLEFALDHAG HLSNTRQFSD
LVDALLIPLV DYDGRTRSIW CYQFRFDFFY AEEVVASRVG QFLSWVSTKL NKRKVKELVT
HRYEDESGST NVIFYLASKH RRSLVEIMLS HLEESDRREI RRIAAASGCL M
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