ID E9G0I6_DAPPU Unreviewed; 690 AA.
AC E9G0I6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN ORFNames=DAPPUDRAFT_44050 {ECO:0000313|EMBL:EFX87396.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX87396.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX87396.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR EMBL; GL732528; EFX87396.1; -; Genomic_DNA.
DR AlphaFoldDB; E9G0I6; -.
DR EnsemblMetazoa; EFX87396; EFX87396; DAPPUDRAFT_44050.
DR KEGG; dpx:DAPPUDRAFT_44050; -.
DR eggNOG; ENOG502QQ46; Eukaryota.
DR HOGENOM; CLU_013435_0_0_1; -.
DR InParanoid; E9G0I6; -.
DR OMA; TENICYC; -.
DR PhylomeDB; E9G0I6; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR InterPro; IPR023608; Transglutaminase_animal.
DR InterPro; IPR008958; Transglutaminase_C.
DR InterPro; IPR036238; Transglutaminase_C_sf.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590:SF52; HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR Pfam; PF00927; Transglut_C; 2.
DR Pfam; PF01841; Transglut_core; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR PIRSF; PIRSF000459; TGM_EBP42; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 252..349
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT ACT_SITE 260
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 323
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 346
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
SQ SEQUENCE 690 AA; 78923 MW; 2782A7FC52477660 CRC64;
MDYRSSSSPS TTVLRRGQPF FMAIRMKDRN FDPRRDILRA SFTFGPNPQV TKGTKVVLPF
RMNQREFSRA PQKWDMRLHQ QEGFNITFQV HIPANALVGL WRVNIETTTT TPGARVDEFR
FKDDIYILFN PFCRDDPVYL DNEELRREYL MNETGKVFVG THHRPKGRRW VYGQFSDVAL
PAAQLLLEQS GLNPTERGNP VQVVRAIASI INANEGFGLL EGKWEGSFED GVCPWVWTGS
NKIFEHYLRN GSKPVKYGQC WVFAAVATSI FRALGIPSRP VTNFVSARDT NHTLSVDKYF
DIFGDEMKGG PDGDNQDAVW NFHAWTEVWM SRPDLQANCN GWQAIDPTPP PHFWQKNTGA
FRRGPSSVES VRRGEVGFAF DTPYLFAEVN AEVSHFQEDE TSHWGYRKIH VNNYQVGRMI
LTKRPGADDD VSDADAEDIT SLYKNPDGIS AAERVSAMNA ARSVERTQPM FDNRPVNEDV
YFDLIEQEKV AWGQPFNLQV LVQNRSQEMR TITTILSANS VYYTGVTARR LGRSDRQFVL
QPGGRETLQV RISWDEYRDK IVDYGHIKIF AMASVQETKQ SWSEEDDFQL EKPKLDVQIR
GNPQVGQDCF ATFSFMNPVS VTLTECEFTF EGPGLVRPQT VKYRDVKPGE MISFAQKFIP
RFNGERKLVA TFNSRELGDI VGSRPIHVRD
//
