ID E9G3V0_DAPPU Unreviewed; 424 AA.
AC E9G3V0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFX85926.1};
DE Flags: Fragment;
GN ORFNames=DAPPUDRAFT_31639 {ECO:0000313|EMBL:EFX85926.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX85926.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX85926.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732531; EFX85926.1; -; Genomic_DNA.
DR AlphaFoldDB; E9G3V0; -.
DR STRING; 6669.E9G3V0; -.
DR EnsemblMetazoa; EFX85926; EFX85926; DAPPUDRAFT_31639.
DR EnsemblMetazoa; XM_046597963.1; XP_046453919.1; LOC124201757.
DR KEGG; dpx:DAPPUDRAFT_31639; -.
DR eggNOG; KOG3508; Eukaryota.
DR HOGENOM; CLU_009167_2_0_1; -.
DR InParanoid; E9G3V0; -.
DR OMA; LMYDEDK; -.
DR PhylomeDB; E9G3V0; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd04013; C2_SynGAP_like; 1.
DR CDD; cd05136; RasGAP_DAB2IP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF125; RAS GTPASE-ACTIVATING PROTEIN RASKOL; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00616; RasGAP; 2.
DR SMART; SM00239; C2; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 1..102
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 160..354
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFX85926.1"
FT NON_TER 424
FT /evidence="ECO:0000313|EMBL:EFX85926.1"
SQ SEQUENCE 424 AA; 48452 MW; 42B61386FE9E397E CRC64;
RRTDNSLKIW ILEAKGVANK KWYFCELCLD KNLHARTAGK QKNDLCFWGQ HFEFDDLPVV
HNININLYRE ADRKKKKDKT FVGTVTIPVN TITSRFLIEK WYPVVSEKGS SKDPPSLRIK
CKYQTVDILP LEVYEEFLEY LKTDYMTVCD LLEPAIGVKA KEDIATALVA VMQREGYAQK
FLADIVMADV DRIDDEHLTF RGNSLATKAM EAYMKLVGEN YLQDTLAEVI GGIVDHAADR
DCEVDPLKVT SPAMLAKQQA HLRAVVESAW HCILKSTPYF PAELQECFYT YRQRLAGFGR
EEVADHLISA SIFLRFLCPA ILSPSLFGIT PEYPSDKAAR NLTLIAKTLQ TLANFTRFQG
KENFMEFMND FLEKEASTMK QYLKEISSPL SKDQCYSKFD DYIDVCKNLS ILHTLFSESL
SKVA
//
