ID E9GDQ7_DAPPU Unreviewed; 508 AA.
AC E9GDQ7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
GN ORFNames=DAPPUDRAFT_241220 {ECO:0000313|EMBL:EFX82122.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX82122.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX82122.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; GL732540; EFX82122.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GDQ7; -.
DR STRING; 6669.E9GDQ7; -.
DR EnsemblMetazoa; EFX82122; EFX82122; DAPPUDRAFT_241220.
DR KEGG; dpx:DAPPUDRAFT_241220; -.
DR eggNOG; KOG1053; Eukaryota.
DR HOGENOM; CLU_007257_4_2_1; -.
DR InParanoid; E9GDQ7; -.
DR PhylomeDB; E9GDQ7; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF24; IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 209..481
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 508 AA; 57633 MW; DAE08150C26A1066 CRC64;
MKIDDDIDDV TTPMAFEPYR FLIPVQDDTA NINAVIKPFQ WPVGTADRIV YLIVLSFVAG
VWCLAAFIFV QAYGDQTADV HTLKVQYAQW PTPPRCLEYV KPRWEGNPKG LSGPLKGGVI
IDYLAARFNF TYEMVRVTEN RMEPLKKERG LFSYLFENQS DLLVVGVPPT HERIKVVDLV
PWAHECYNFL VAVHDDSANF KAVIKPYQWP VWLGIAISMI CVIAVLYSIQ WYLDRHSHQS
LTSQQMSHRR STLVGKHYLY VFGNLVTQGG PCTSKRLPFR LVAGVWTLAA FIFVQAYNSI
LFTYVVATVN RPLINSINDI LDSNDIQLLD PNATGVFLKI KKNLNSTPNS RCNLVSECIS
WVTPGSRKVF ADARSQQLDA IKDNYEKTGK CGLQLAKECF MSTTVGMALQ KHSRYTDTIN
MGLLQLQQTG IIDYWDLWFR KMPLQCSANI NSEYSKKPST VHSSLSLKNL TGAFVVLLIG
FSCSLFVFLC EQITKFARRH CRASMQQL
//
