ID E9GJ93_DAPPU Unreviewed; 501 AA.
AC E9GJ93;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN ORFNames=DAPPUDRAFT_51170 {ECO:0000313|EMBL:EFX80526.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX80526.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX80526.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; GL732547; EFX80526.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GJ93; -.
DR SMR; E9GJ93; -.
DR STRING; 6669.E9GJ93; -.
DR EnsemblMetazoa; EFX80526; EFX80526; DAPPUDRAFT_51170.
DR EnsemblMetazoa; XM_046597442.1; XP_046453398.1; LOC124201007.
DR KEGG; dpx:DAPPUDRAFT_51170; -.
DR eggNOG; KOG2450; Eukaryota.
DR HOGENOM; CLU_005391_0_1_1; -.
DR InParanoid; E9GJ93; -.
DR OMA; ILMGAWK; -.
DR PhylomeDB; E9GJ93; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IBA:GO_Central.
DR CDD; cd07141; ALDH_F1AB_F2_RALDH1; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF302; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 29..492
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 269
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 501 AA; 54614 MW; 74F1DC8506BAD1F2 CRC64;
MSAAPSSGLP SPQTNPEILY TGVFINNEWH NSVSGKTFPV YNPSTGEAIA NIQAAEKEDV
NKAVKAAQNA FQLGSTWRTM NASSRGNLLN RLADLMERDR VYLASLETLN NGKPYSAAYA
ADLELSIKCL RYYAGWADKV QGKTIPVDGS FFAFTRHEPV GVCGQIIPWN FPLLMQAWKL
GPALATGNTV VMKPAEQTPL TALYVAELIK EAGFPPGVVN IVPGFGPTAG AAIASHKGVD
KVAFTGSTEI GHLVMTAAAQ SNLKRVTLEL GGKSPNIIFK DCDLDHAVET AHFGLFFNQG
QCCCAGSRIF VEDSIYDEFV ERSVERAKKR NVGNPFDLNV EQGPQVDEDQ FKKILALIDT
GKREGAKLLT GGQRYGDRGY FIQPTVFADV KDDMTIAREE IFGPVQQILK FSSMEEIVER
ANKTIYGLAA AVFTKDLDKA MYLSQGLRAG TVWINCYDVL EAQTPFGGFK MSGIGRELGE
YGLQAYTEVK SVIVKMPQKN S
//
