ID E9GJA7_DAPPU Unreviewed; 827 AA.
AC E9GJA7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Dipeptidyl peptidase 9 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_304113 {ECO:0000313|EMBL:EFX80414.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX80414.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX80414.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732547; EFX80414.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GJA7; -.
DR STRING; 6669.E9GJA7; -.
DR ESTHER; dappu-e9gja7; DPP4N_Peptidase_S9.
DR EnsemblMetazoa; EFX80414; EFX80414; DAPPUDRAFT_304113.
DR KEGG; dpx:DAPPUDRAFT_304113; -.
DR eggNOG; KOG2281; Eukaryota.
DR HOGENOM; CLU_006105_1_0_1; -.
DR InParanoid; E9GJA7; -.
DR OMA; VTHMTPQ; -.
DR PhylomeDB; E9GJA7; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0008239; F:dipeptidyl-peptidase activity; IBA:GO_Central.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 165..536
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 626..827
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 827 AA; 93931 MW; 6C15131727153881 CRC64;
MEDNHLVNNP RTKNWGDSKQ AVRELRRQIS CLSSRVPSTF SFRQLSPSVI RIYFLCSPSN
GRETTLFFCD VDATLAWELE GSPLVWHAAI DPNFQVMPSV GKFSKEEQLQ WERKRLVTSG
ITSYELHHES GRLIFPAGGS MFQCMDPGNH IVNLQPIQLE TNCGGARLNC QISPNFSELV
AFVSNSDVWV AHTESGNEQR LTWVHTNKNS LAADPLSAGI PSYVIQEEFC RFQGFWWQPV
MTDGIFRILI EEVDESDVGI IKFPSFNGDG GMEEYRFPRA GTPNAKSDLK MVSFQLNEKN
EFVDIQLLEL PQPLGIMFPS AEYLTRAGWT PQGDHVWVQL VDRLQQKLDL VLIPLHFFRP
CRATRRANFI ETSTSLSPIC RLPAQMLCSV FSQNWINVHD ILHFLPMDEP DMMRFIFASE
ETGYRHLYLY TVQLAVSPNK ASITDGVCRA TQVDKQSLTS GEWEVLDQWL WVDHKFGLVY
FMGLRDSPLS SHLYVTSYNR PGSNIVRLTQ NGYSHTVSMN KECTIFVTVY SNTQSMPACQ
VVALEPPADL VHPVPLAFLV EPALPDQWYQ PPELFSHVIS SGDRLHGMIF RPHNYRPGTK
YPTVLNIYGG PEVQLVTNTF KGLRQLRLHM LAALGYCVVT IDSRGSQNRG VNFESHIKGR
LGTVELHDQV EVLQWVAETM SCIDLNRVAI HGWSYGGYLS LLGLAQYSHV FKVAIAGAPV
TSWNLYDTGY TERYLGQPQT NQIGYKNGSV LSYVNQFPDQ ENRLLIIHGM IDENVHFAHT
SQLINALVRS GKPYQLQVYP NERHSLRHLD ASEHYETVLL TFLRNCL
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