ID E9GVI3_DAPPU Unreviewed; 274 AA.
AC E9GVI3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=CCR4-Not complex component Not N-terminal domain-containing protein {ECO:0000259|Pfam:PF04065};
GN ORFNames=DAPPUDRAFT_198891 {ECO:0000313|EMBL:EFX76526.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX76526.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX76526.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682}.
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DR EMBL; GL732568; EFX76526.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GVI3; -.
DR STRING; 6669.E9GVI3; -.
DR EnsemblMetazoa; EFX76526; EFX76526; DAPPUDRAFT_198891.
DR EnsemblMetazoa; XM_046592582.1; XP_046448538.1; LOC124197234.
DR KEGG; dpx:DAPPUDRAFT_198891; -.
DR eggNOG; KOG2150; Eukaryota.
DR HOGENOM; CLU_073755_0_0_1; -.
DR InParanoid; E9GVI3; -.
DR OMA; CECKIES; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04065; Not3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..231
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT COILED 41..68
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 274 AA; 32418 MW; E6357A6703DC6EAB CRC64;
MAATRKLQGE IDRCLKKVTE GVELFEDIWQ KVHNAANSNQ KEKYETDLKK EIKKLQRLRD
QIKSWIQSAE IKDKSQLVEN RKLIETQMER FKIVERETKT KAYSKEGLGA AQKLDPAQKE
REDISQWLNT SIENLNIQID QFECEIESLL AAKKKKLDKD KQERLDKLKE FLERHRFHIR
KLETLLRMLD NLTVEVTQIK KIKDDIEYYI EAASTDPDFE ENTYLYDDIN FLDEFADVVG
TVGGNFWSCF VLFSFLSSLL GFNWNSNWIM FEVK
//
