ID E9GXR1_DAPPU Unreviewed; 200 AA.
AC E9GXR1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Spaetzle domain-containing protein {ECO:0000259|Pfam:PF16077};
GN ORFNames=DAPPUDRAFT_107622 {ECO:0000313|EMBL:EFX75770.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX75770.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX75770.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732573; EFX75770.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GXR1; -.
DR STRING; 6669.E9GXR1; -.
DR EnsemblMetazoa; EFX75770; EFX75770; DAPPUDRAFT_107622.
DR KEGG; dpx:DAPPUDRAFT_107622; -.
DR HOGENOM; CLU_1367481_0_0_1; -.
DR InParanoid; E9GXR1; -.
DR PhylomeDB; E9GXR1; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IEA:UniProt.
DR GO; GO:0008083; F:growth factor activity; IBA:GO_Central.
DR GO; GO:0005121; F:Toll binding; IBA:GO_Central.
DR GO; GO:0021556; P:central nervous system formation; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR032104; Spaetzle.
DR PANTHER; PTHR23199:SF12; NEUROTROPHIN 1-RELATED; 1.
DR PANTHER; PTHR23199; UNCHARACTERIZED; 1.
DR Pfam; PF16077; Spaetzle; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 95..195
FT /note="Spaetzle"
FT /evidence="ECO:0000259|Pfam:PF16077"
SQ SEQUENCE 200 AA; 22663 MW; B1A01689F9DE0C5E CRC64;
MQMLVSLGVV AVMGNNYKPP AYHQPKYEPK YEPEIPACSK NTTKNWCLED SEYPAYEVVY
ELDKHYEAVV ALYKNVVAET ANSVDTLTKL VDETYLCPSA TSYVQPLRAV NTKGKWRVII
NKVESYGIKY DQHARIEECE ADAAGKACPL VPTCYESKCL QKSIYHRFLV FDPTDYYFPF
AIETFKLPAS CACFVGAFSL
//
