ID E9H0H8_DAPPU Unreviewed; 748 AA.
AC E9H0H8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Septin-type G domain-containing protein {ECO:0000259|Pfam:PF00735};
GN ORFNames=DAPPUDRAFT_251468 {ECO:0000313|EMBL:EFX74807.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX74807.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX74807.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR EMBL; GL732580; EFX74807.1; -; Genomic_DNA.
DR AlphaFoldDB; E9H0H8; -.
DR STRING; 6669.E9H0H8; -.
DR EnsemblMetazoa; EFX74807; EFX74807; DAPPUDRAFT_251468.
DR KEGG; dpx:DAPPUDRAFT_251468; -.
DR eggNOG; ENOG502QTS0; Eukaryota.
DR HOGENOM; CLU_018951_2_0_1; -.
DR InParanoid; E9H0H8; -.
DR PhylomeDB; E9H0H8; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0031105; C:septin complex; IBA:GO_Central.
DR GO; GO:0005940; C:septin ring; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0061640; P:cytoskeleton-dependent cytokinesis; IBA:GO_Central.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR32046; G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR32046:SF14; IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE; 1.
DR Pfam; PF00735; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 247..329
FT /note="Septin-type G"
FT /evidence="ECO:0000259|Pfam:PF00735"
FT REGION 133..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 637..664
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 707..734
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 133..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 84820 MW; 318A04DF2B1FBF0B CRC64;
MRYFTDMDYF QIQYEILGQL FENARDNASE IVRIYFTMIG HKDFQSSNLI YLNQKAVLLL
SPEVVDVLKN NRLDAFSYLL VANNLLNLED VKEDLLNGDV LAKATPSNSI RRLKAELGLA
TNLMDQIAAV PDTSKPISPQ QQLPENASVA PTVPDDKTHP INQQQQPKED ATAANLCENI
QRESIAAEVI NRLPFEIKNE CTESTDVEGV TLYKLKLTQV PTYTESSSMV KRFSFGEPIL
TDRKRKTILL MGATGSGKTT MINAMINYVL GVEWDDPFRF ILVDEELRGA SQANSQTQGV
TAYDLHYRNG FRIPFSLTIV DTPGFGDTGG MERDKEITSA IQEFFKHQNG IQELDAVGFV
VQSSLVRLTA SQKYIFNSVL SIFGKDIEEN IRFLVTFSDG RQPLVLDAIN EAQLPCRMDS
KGLPSHQKFN NGAVFISQSD EDDMSPVEWK NAMKNFKLFF EEINEMPTKS LQMTNQVLED
REQLEIYLDF MLGGIEKQLM KVDELCKTKD LVAINRDKIQ ANQNFEMSVP VSKKVKMPTD
RLAMNCTKCE TTCHYPCEPS LLTGFCSAFW KSEGIVIQND FIVLANTLIN AAKNLAAPKC
KICPGRCSDG LHRNEHFKWT FIQVEEMRTF YDIRNNYEDA TKKKMDAETL VKAVETEVEK
LKEETIKNMN GITYLHNKLK AIALHGNPLS TFEYIQMMVD NAERDQKPGC REKIQNLQEL
LELAKNNGNN IDDDEKFVKQ FTSLNSSS
//
