ID E9H7J9_DAPPU Unreviewed; 421 AA.
AC E9H7J9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Cell division control protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_227580 {ECO:0000313|EMBL:EFX72296.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX72296.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX72296.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family.
CC {ECO:0000256|ARBA:ARBA00006184}.
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DR EMBL; GL732601; EFX72296.1; -; Genomic_DNA.
DR AlphaFoldDB; E9H7J9; -.
DR STRING; 6669.E9H7J9; -.
DR EnsemblMetazoa; EFX72296; EFX72296; DAPPUDRAFT_227580.
DR KEGG; dpx:DAPPUDRAFT_227580; -.
DR eggNOG; KOG2227; Eukaryota.
DR HOGENOM; CLU_012774_3_1_1; -.
DR InParanoid; E9H7J9; -.
DR OMA; NCEVIDT; -.
DR PhylomeDB; E9H7J9; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR GO; GO:0033314; P:mitotic DNA replication checkpoint signaling; IBA:GO_Central.
DR CDD; cd00009; AAA; 1.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR041083; AAA_lid_10.
DR InterPro; IPR016314; Cdc6/18.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10763:SF26; CELL DIVISION CONTROL PROTEIN 6 HOMOLOG; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF17872; AAA_lid_10; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR PIRSF; PIRSF001767; Cdc6; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 53..195
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 324..404
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
SQ SEQUENCE 421 AA; 46275 MW; ABBBE0B52AEDDDAF CRC64;
MKLQNPNGDL TVTSNFTKAR QALHTSTPGN IFCRDKELDI IETFLQNHID NGTSGSMYIS
GRPGTGKTAC VTHILANRTF SGKFKSILIN CMLLHTPTSV FQQVAQQLDP KWNTTAKEAL
SYLEDRLTES GPMIVLVLDE IDQMSTRDQS VLYALFELPA LTNSRLILIG LANALDLTDR
SLIRLQSRVH FKPVLLNFSP YSKQEIATIV SQRIQEAVGE DVGNVIAPSA LQYLGGKISS
TSGDLRKAID ICRRAVELAE TGAKKQSVLA SSNSELQTSE SVQTNKCVSI PILCKMMASV
ESNAFSVGNS DDVDDTPLQQ KLIIVTLLVL VKFGKSKQVT LGKLHQSYSK VCSKYGMTTI
DFDEFSHTCS LVESRGIVIL KRKSNPRLAP ICLRLDEREV ESTLKDKTLL SSILAQGSLF
V
//
