ID E9HCD4_DAPPU Unreviewed; 619 AA.
AC E9HCD4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=PPIase cyclophilin-type domain-containing protein {ECO:0000259|PROSITE:PS50072};
GN ORFNames=DAPPUDRAFT_309393 {ECO:0000313|EMBL:EFX70629.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX70629.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX70629.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732619; EFX70629.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HCD4; -.
DR STRING; 6669.E9HCD4; -.
DR EnsemblMetazoa; EFX70629; EFX70629; DAPPUDRAFT_309393.
DR KEGG; dpx:DAPPUDRAFT_309393; -.
DR eggNOG; KOG0882; Eukaryota.
DR HOGENOM; CLU_012062_31_2_1; -.
DR InParanoid; E9HCD4; -.
DR OMA; GMVEYWR; -.
DR PhylomeDB; E9HCD4; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:GO_Central.
DR CDD; cd01927; cyclophilin_WD40; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR InterPro; IPR044666; Cyclophilin_A-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR45625; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED; 1.
DR PANTHER; PTHR45625:SF4; PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00160; Pro_isomerase; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00153; CSAPPISMRASE.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 103..144
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 463..618
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 69888 MW; 4C8C855B22AD4312 CRC64;
MAESTSTKRQ HEENNSESDD EFVGPLPSEA VQTKAKKKKV LEFEDLYLDN LPNVEMYERS
FMHRDVVTHL VTTKTNFIIT CSIDGHIKFW KKQELGIEFV KHFRGHLGNI QDVGINSSGT
LLCTISNDKS LKVFDVVNFD MINMMKLSYI PGCCEWVHSP GDPVSVLAVS DSENGIINLY
DGHGINKPIH QIEKLHTKPV TLIKYNAVYE AVVSVDKQGI LNYWTGEKSD YAFPKNVDFD
SKLDTDLFEF VKQKTYPLSL CFSPNGELFA TYGADRKVRI FKFATGKLSR VIDESIQHYT
ELQQKKALPN MEFNRRVAME KEVEKTDCLH FTRLTFDESG HFLLVPTMIG IKVINLVTNR
LARLIGKPEN MRFLQLSLIQ GKARHNPAAV TLEMEASENP TLESIEPDST LFVTAFKKNR
FFLFTRRDPD DSKAPGTERD IFNEKPSKED MIAATDAIGT QRIYDTAVLH TTVGDVHIQL
FGKECPKTIE NFCVHSKNGY FNNHIFHRCI KGFMIQTGDP LGTGTGGESI WGGEFGDEFH
PSLRHDRPYT VSMANAGPGT NGSQFFITVA PAPWLDNKHT VFGRVVKGME VVQEISSTKT
NPKTDKPYND ISIISVTVK
//
