ID E9HG77_DAPPU Unreviewed; 513 AA.
AC E9HG77;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Calmodulin-binding domain-containing protein {ECO:0000259|SMART:SM01053};
GN ORFNames=DAPPUDRAFT_258886 {ECO:0000313|EMBL:EFX69273.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX69273.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX69273.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL732639; EFX69273.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HG77; -.
DR STRING; 6669.E9HG77; -.
DR EnsemblMetazoa; EFX69273; EFX69273; DAPPUDRAFT_258886.
DR KEGG; dpx:DAPPUDRAFT_258886; -.
DR eggNOG; KOG3684; Eukaryota.
DR HOGENOM; CLU_014617_5_0_1; -.
DR InParanoid; E9HG77; -.
DR OMA; PLFAIKC; -.
DR PhylomeDB; E9HG77; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0043025; C:neuronal cell body; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR004178; CaM-bd_dom.
DR InterPro; IPR036122; CaM-bd_dom_sf.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR Pfam; PF02888; CaMBD; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF03530; SK_channel; 1.
DR PRINTS; PR01451; SKCHANNEL.
DR SMART; SM01053; CaMBD; 1.
DR SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 391..464
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000259|SMART:SM01053"
SQ SEQUENCE 513 AA; 58432 MW; 87C1A683EEA3DF6B CRC64;
MQCEFSMAAI EGSESEENVR PSAGRCNGGN PNALREITIS ATASTAKVKS DFASGVEFKS
ITSYSGSRTA VRPLTAMSKN RSNAGYQIGR RKELFEKRKL ISDFALVFGI FGIIVMVIES
ELASYGFYTK LSFYSSTLKT LISVSTVVLL GLIVTYHVFA VQIFLIQNCV DDWRIAMTWK
RIIQITLELL FFAVHPIPGE LNFFWTTNHI IGDVTESKLV PVDVVLSLPM FLRCYLIGRV
MLLHRHNLEI DRCLQSDFFD KRFILKTLMT IRPGTVLLVV MGSLWIIISW TMRQCERYHN
EEHDNLLNTM WMIVITFLTI GYGDMFPRTY CGRGIAVATG FLGAGCTALL VAVLTNKLEL
TQAEKHVHNL MRDTQLNKEL VCGPIYYSAM NIQSRQLKNA AANVLRETWL IYKYKKLVDC
VNPGRVRTHQ RKFLLAIYSL RKAKLDRRKL MDNTGVDMAK NNISTEIILE MNARQKIMFE
RLGMLEKKLS VLQETVEALP ETAFRHQTNF FNS
//
