ID E9HJS1_DAPPU Unreviewed; 690 AA.
AC E9HJS1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=DAPPUDRAFT_330505 {ECO:0000313|EMBL:EFX68020.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX68020.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX68020.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732664; EFX68020.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HJS1; -.
DR STRING; 6669.E9HJS1; -.
DR EnsemblMetazoa; EFX68020; EFX68020; DAPPUDRAFT_330505.
DR KEGG; dpx:DAPPUDRAFT_330505; -.
DR eggNOG; ENOG502QQ8V; Eukaryota.
DR HOGENOM; CLU_006994_2_1_1; -.
DR InParanoid; E9HJS1; -.
DR OMA; SAVCWKQ; -.
DR PhylomeDB; E9HJS1; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd16504; RING-HC_COP1; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR042755; COP1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR44080; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR PANTHER; PTHR44080:SF1; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR Pfam; PF00400; WD40; 4.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00184; RING; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 119..157
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 462..504
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 548..588
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 240..274
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 690 AA; 77682 MW; 314D5CCB3CA56450 CRC64;
MAASITQVFR VNSCRLLYCN RFSKVAFPAF STQATNLKKG KGLILGGYSS KKTETDVDAT
KDFIWTQAAK SFNDQVANRL NDALNCLKMA GRGVKRGPQS LLFGGVKDTY EDRDSDLLCP
VCLDMMSEPY VTTCGHSFCH GCIVRSLELA SKCPKCSGPL DSSGRNPSVF PNVTLNALIT
KQKKKLVESQ DGNILMKDFT TLLDTRDWHP SELVRMQEVL LRKQCDLDGE RKLTEAQLLN
EFLQQLKTKK NNELRNVQQE LEVLDKDLNM AQTLNPGIDS AAIKVENYEV NETAFNSSIA
STPLSIGQRR VRMHQHFEDL EGKYWALRNN RLNGEEEEKK SLLDFQSNLN QLTRWSRLRP
LANLSYGSEL LNTAHIVSSI EFDRDADFFA IAGVTKRIKV YDYAVVVRDA VDLHYPVMEM
VAGSKISCIS WSAYHKSVLA SSDYEGSVSV WDASVGTRLR VFQEHEKRCW SVDFNRMDSH
LMASGSDDSR VKIWSLNAEH SVATLEAKAN VCCVKFNPYS RYCLAYGAAD HCVHYVDLRQ
PKEPLRVFKG HRKAVSYVKF LSDRELVSAS TDSQLKLWTV EDNVSCRSFR GHTNEKNFVG
LSTTDGSQDD RRDLIACGSE NNALYLYSKG LSQPLLHYRF DVVKSALLLD KERAEQEESA
EFVSAVCWKP DSNVIVAANS QGTIKILELV
//
