ID E9HXT0_DAPPU Unreviewed; 316 AA.
AC E9HXT0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=DAPPUDRAFT_335441 {ECO:0000313|EMBL:EFX63450.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX63450.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX63450.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; GL733070; EFX63450.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HXT0; -.
DR EnsemblMetazoa; EFX63450; EFX63450; DAPPUDRAFT_335441.
DR KEGG; dpx:DAPPUDRAFT_335441; -.
DR eggNOG; ENOG502S73E; Eukaryota.
DR HOGENOM; CLU_788138_0_0_1; -.
DR InParanoid; E9HXT0; -.
DR OMA; WITTTIC; -.
DR PhylomeDB; E9HXT0; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IBA:GO_Central.
DR GO; GO:0043137; P:DNA replication, removal of RNA primer; IBA:GO_Central.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 19..153
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 316 AA; 35082 MW; 5C20C99CC4A159F8 CRC64;
MVPSQQTTSP FNTLDSSAPA TSIRAYTDGS KSSSQETTTC AIFIPALNKE HVWTLTKGSS
IFTAEVTAIY QALKLFYDMD DCPPEAIIYS DSSSAITAIS SNSLSENEAI TATREIIASL
KSSGTRTRLT WIPSHTGIEG NERADRLAAT ECNTQDGEEV HNSLSPKEMV SIIRANWATN
LLRNQKTCKK SCIQMRSRQG TIKWHQHPNR QVAICLHRLR SGHNRLNAFS HRIDPEADPS
CRVGCAAIEN ARHILESCSR NEEFGLKIRQ FFSDRNLELN ASTMFGLNPA IDADTQFKIR
NLTTQFLTQS ALINII
//
