ID E9IL86_SOLIN Unreviewed; 327 AA.
AC E9IL86;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=polo kinase {ECO:0000256|ARBA:ARBA00012424};
DE EC=2.7.11.21 {ECO:0000256|ARBA:ARBA00012424};
DE Flags: Fragment;
GN ORFNames=SINV_04409 {ECO:0000313|EMBL:EFZ18664.1};
OS Solenopsis invicta (Red imported fire ant) (Solenopsis wagneri).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Solenopsis.
OX NCBI_TaxID=13686;
RN [1] {ECO:0000313|EMBL:EFZ18664.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21282665; DOI=10.1073/pnas.1009690108;
RA Wurm Y., Wang J., Riba-Grognuz O., Corona M., Nygaard S., Hunt B.G.,
RA Ingram K.K., Falquet L., Nipitwattanaphon M., Gotzek D., Dijkstra M.B.,
RA Oettler J., Comtesse F., Shih C.J., Wu W.J., Yang C.C., Thomas J.,
RA Beaudoing E., Pradervand S., Flegel V., Cook E.D., Fabbretti R.,
RA Stockinger H., Long L., Farmerie W.G., Oakey J., Boomsma J.J., Pamilo P.,
RA Yi S.V., Heinze J., Goodisman M.A., Farinelli L., Harshman K., Hulo N.,
RA Cerutti L., Xenarios I., Shoemaker D., Keller L.;
RT "The genome of the fire ant Solenopsis invicta.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:5679-5684(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000540};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.21; Evidence={ECO:0000256|ARBA:ARBA00000856};
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DR EMBL; GL764029; EFZ18664.1; -; Genomic_DNA.
DR AlphaFoldDB; E9IL86; -.
DR EnsemblMetazoa; XM_026138060.2; XP_025993845.1; LOC105195386.
DR HOGENOM; CLU_850781_0_0_1; -.
DR OMA; GENIHYI; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13118; POLO_box_1; 1.
DR CDD; cd13117; POLO_box_2; 1.
DR Gene3D; 3.30.1120.30; POLO box domain; 2.
DR InterPro; IPR033701; POLO_box_1.
DR InterPro; IPR033695; POLO_box_2.
DR InterPro; IPR000959; POLO_box_dom.
DR InterPro; IPR036947; POLO_box_dom_sf.
DR PANTHER; PTHR24345; SERINE/THREONINE-PROTEIN KINASE PLK; 1.
DR PANTHER; PTHR24345:SF0; SERINE_THREONINE-PROTEIN KINASE PLK1; 1.
DR Pfam; PF00659; POLO_box; 2.
DR SUPFAM; SSF82615; Polo-box domain; 2.
DR PROSITE; PS50078; POLO_BOX; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 148..211
FT /note="POLO box"
FT /evidence="ECO:0000259|PROSITE:PS50078"
FT DOMAIN 246..314
FT /note="POLO box"
FT /evidence="ECO:0000259|PROSITE:PS50078"
FT NON_TER 327
FT /evidence="ECO:0000313|EMBL:EFZ18664.1"
SQ SEQUENCE 327 AA; 37502 MW; 616D1A2B99E64C0C CRC64;
MNMVANMLQL NPSKRPSVAK LMKDIFFTSG YLPTSLPLSC LSTAPRLDML ESHCNRKPLG
EMNLNGYSEQ DILASRVPNS PLRKVKPNNE IAEPQRVSLD IRKMLHTLKE QIAMVLKTKP
ARETASSADE LTDPAAQPVI WISKWVDYSD KYGFGYQLSD DSVGVMYNDG TRLIMMANGY
NIHYINREGD ELYYTVKEYP TNLEKKMKLM NFFLKYMNEH LMKAGGSIAV KQSDSLSRIP
YIHQWFRTQT AVVMQLTNGT VQINFLDHAK IIMCPLMTAV TYIDHDKNFK TYRFQTIQEN
GCCKGLADNL MYAYEKIRLM LTNSQTR
//
